Search

everythingexperts & clinicslearnresearchcommunity

for

Search:↓

Deleting the scd1 gene in mice prevents obesity by disrupting skin lipids and improving heat regulation.

SIRT1-modified stem cells can help treat peritoneal fibrosis by blocking a harmful pathway.

11β-Hydroxylase inhibitors help prevent seizures in mice by boosting natural neurosteroid production.

SCD1 is important for hair growth by keeping the connection in skin cells where hair stem cells live stable.

DA-9401 can protect against finasteride-induced reproductive damage in rats.

Reducing neurosteroid levels worsens brain injury in fetal sheep.

Dietary L-serine supplementation can reduce symptoms of HSAN1 by lowering harmful 1-deoxySL levels.

FR-1 reduces skin scarring and promotes healing without harmful effects.

Blocking CISD1 reduces hearing loss from cisplatin in mice.

Danoprevir, remdesivir, and saridegib may effectively inhibit SARS-CoV-2.

CS-891 may effectively treat hair loss by blocking enzymes in hair follicles.

Finasteride helps female-pattern hair loss.

The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.

Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.

Antisense oligonucleotides show promise for treating Myotonic Dystrophy type I.

Blocking LFA-1 prevents hair loss in mice.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

Silicate-based therapy may help treat inflammatory heart disease by reducing immune inflammation.

Ca²⁺-mediated protein citrullination controls cell growth in the CNS and may help treat brain tumors.

DKK2 and SOSTDC1 together are necessary for the normal timing of the first regression phase in the hair growth cycle.

This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.

Zinc sulfide cellulose scaffolds can reduce scarring and promote hair growth.

Neurosteroids and benzodiazepines reduce neuron excitability, with lasting effects on inhibitory neurons.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Increasing Smurf2 hinders hair follicle stem cell differentiation and wound healing.