16 citations
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February 2005 in “British journal of dermatology/British journal of dermatology, Supplement” Lack of Vitamin D receptor changes skin structure and increases certain immune cells in the skin.
9 citations
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January 2015 in “Medical hypotheses” TCDD disrupts skin stem cells, causing skin issues like chloracne.
1 citations
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May 2012 in “International Conference on Biomedical Engineering and Biotechnology” TGF-β receptor 1 helps deer antlers grow by aiding skin and cartilage cell growth.
January 2012 in “Chinese Journal of Aesthetic Medicine” Increased androgen receptor expression in certain hair follicle areas may cause male pattern baldness.
21 citations
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November 2022 in “Frontiers in immunology” Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
125 citations
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February 2007 in “The EMBO Journal” Fgfr2b helps maintain healthy skin and prevent cancer.
124 citations
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December 1983 in “Developmental Biology” EGF receptors are crucial for skin cell growth and decrease with age.
59 citations
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January 2005 in “Endocrine Journal” Sex steroids influence skin appendage function and neoplasm development, with changes in AR and ERalpha in certain gland neoplasms.
48 citations
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March 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Retinoic acid production and signaling in hair follicles are regulated by location and timing, affecting hair growth and cycling.
40 citations
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April 1995 in “Journal of Cutaneous Pathology” Androgen receptors are found in some skin tumors but not in hair follicle tumors.
39 citations
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September 2007 in “BMC developmental biology” Neuregulin3 affects cell development in the skin and mammary glands.
26 citations
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October 1996 in “Journal of Endocrinology/Journal of endocrinology” Goat hair follicles have insulin-like growth factor-I receptors that might affect hair growth, but no melatonin receptors were found.
13 citations
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April 1994 in “Journal of Investigative Dermatology” Androgen receptors found in monkey scalps, similar to humans, affect hair growth.
11 citations
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May 2010 in “Journal of Medicinal Chemistry” A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.
9 citations
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April 2021 in “Expert opinion on pharmacotherapy” Clascoterone is a new, effective, and safe acne treatment without systemic side effects.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Different types of PPARγ are found in varying amounts in human skin and its parts, which could affect how skin treatments work.
73 citations
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June 2001 in “Endocrinology” Prolactin affects when mice shed and grow hair.
14 citations
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June 2001 in “Endocrinology” Prolactin affects when mice shed and grow hair.
53 citations
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July 2009 in “Cancer Research” Blocking certain proteins can reduce skin inflammation caused by cancer treatment.
22 citations
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June 2010 in “Experimental Dermatology” Lower MC2R expression may contribute to alopecia areata.
January 2014 in “Medical Innovation of China” Androgen receptor differences may contribute to hair loss in AGA patients.
July 2024 in “Journal of Investigative Dermatology” Losing both ERBB2 and ERBB3 receptors in mice causes significant skin problems and inflammation.
466 citations
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June 2009 in “Experimental dermatology” We now understand more about what causes acne and this could lead to better, more personalized treatments.
34 citations
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April 2018 in “EMBO journal” The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.
18 citations
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June 2012 in “Archives of Dermatological Research” Vitamin D boosts a specific protein in skin cells linked to hair follicles.
9 citations
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August 2021 in “Experimental dermatology” Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.
9 citations
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September 2009 in “PubMed” Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.
4 citations
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May 2012 in “Journal of Investigative Dermatology” The symposium concluded that a specific lipid might cause hair loss, inflammation is a key factor, and stem cells in bald scalps aren't working right, suggesting new treatment targets.
April 2016 in “Journal of Investigative Dermatology” A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.
55 citations
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January 2002 in “Journal of liposome research” New liposomal formulations may improve delivery of treatments to hair follicles, potentially helping with hair loss.