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GlossarySecondary Hair Follicles

smaller hair-producing structures that develop alongside primary follicles

Secondary hair follicles are smaller hair-producing structures that develop alongside primary hair follicles, typically in mammals with dense fur or wool. They produce finer, shorter hairs that contribute to the overall thickness and insulation properties of the animal's coat. These follicles are crucial for maintaining the density and texture of the fur, especially in species adapted to cold environments.

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Effect of Body Weight Gain During Cashmere Non-Growing Period on Cashmere Production Performance and Secondary Hair Follicle Activity of Cashmere Goats

research Effect of Body Weight Gain During Cashmere Non-Growing Period on Cashmere Production Performance and Secondary Hair Follicle Activity of Cashmere Goats

2 citations , September 2023

Gaining 5-10 kg during the non-growing period boosts cashmere yield and length in goats.

research Effect of Fasted Live-Weight Gain during the Cashmere Non-Growing Period on Cashmere Production Performance and Secondary Hair Follicle Activity of Cashmere Goats

November 2023 in “Animals”

Feeding goats more during the non-growing period increases cashmere yield and length.

Fibroblast Growth Factor 5-Short (FGF5s) Inhibits the Activity of FGF5 in Primary and Secondary Hair Follicle Dermal Papilla Cells of Cashmere Goats

research Fibroblast growth factor 5-short (FGF5s) inhibits the activity of FGF5 in primary and secondary hair follicle dermal papilla cells of cashmere goats

42 citations , September 2015 in “Gene”

FGF5s can block the effects of FGF5, which may help control hair growth in cashmere goats.

research The influence of biotin on viability, pyruvate carboxylase activity and the response to malate concentration in vitro by isolated secondary hair follicles of the Angora goat

January 1999 in “Proceedings of the British Society of Animal Science”

Biotin deficiency may harm hair follicle health and growth in Angora goats.

Effects of Photoperiod on Nutrient Digestibility, Hair Follicle Activity, and Cashmere Quality in Inner Mongolia White Cashmere Goats

research Effects of photoperiod on nutrient digestibility, hair follicle activity and cashmere quality in Inner Mongolia white cashmere goats

11 citations , August 2018 in “Asian-Australasian journal of animal sciences”

Short daily photoperiods improve cashmere production in Inner Mongolia white cashmere goats.

Seasonal Variation in Hair Follicle Activity and Fiber Growth of Both Male and Female Merghoz Goats in Western Iran

research Seasonal variation in hair follicle activity and fibre growth of both male and female Merghoz goats in Western Iran

5 citations , October 2011 in “Small ruminant research”

Goat hair growth and follicle activity change with the seasons and differ between males and females.

Mitotic Processes in Hair Follicles and the Morphostructure of Sheep Skin Upon Inclusion of a Water-Soluble Fatty Acid Complex Into Their Diets

research Mitotic processes in hair follicles and the morphostructure of sheep skin upon inclusion of a water-soluble fatty acid complex into their diets

April 2025 in “Ukrainian Journal of Veterinary and Agricultural Sciences”

Adding a water-soluble fatty acid complex to sheep diets improves wool growth by increasing primary hair follicle size and density.

Determination of Secondary Follicle Characteristics, Density, Activity, and Hoxc13 Expression Pattern of Hexi Cashmere Goat Breed

research Determination of Secondary Follicle Characteristics, Density, Activity, and Hoxc13 Expression Pattern of Hexi Cashmere Goats Breed

7 citations , June 2015 in “The anatomical record”

Hexi cashmere goats' hair growth varies by stage, with Hoxc13 linked to hair activity.

research Increasing GSH-Px Activity and Activating Wnt Pathway Promote Fine Wool Growth in FGF5-Edited Sheep

June 2024 in “Cells”

Editing the FGF5 gene in sheep increases fine wool growth.

research Seasonal Gene Expression Profile Responsible For Hair Follicle Development In Angora Goats

2 citations , March 2022 in “Research Square (Research Square)”

Seasonal changes affect gene activity linked to hair growth in Angora goats, influencing mohair quality.

Effects of Photoperiod Change on Serum Hormone Levels, Hair Follicle Growth, and Antioxidant Status in Skin Tissue of Cashmere Goats

research Effects of photoperiod change on serum hormone level, hair follicle growth and antioxidant status in skin tissue of cashmere goats

March 2025 in “Frontiers in Veterinary Science”

Changing light exposure boosts hormone levels and antioxidant activity, improving cashmere growth in goats.

research Growth and viability of Liaoning Cashmere goat hair follicles during the annual hair follicle cycle

10 citations , January 2014 in “Genetics and Molecular Research”

Liaoning Cashmere goat hair follicles show synchronized growth patterns with lowest activity in May.

Age-Related Variations in the Population of Active Secondary Hair Follicles, Oxidative Stress, and Antioxidant Parameters in Cashmere Goats

research Age-Related Variations in the Population of Active Secondary Hair Follicles, Oxidative Stress and Antioxidant Parameters in Cashmere Goats

April 2024

Younger goats produce more cashmere and have healthier hair follicles due to better antioxidant capacity.

research Age-Related Variations in the Population of Active Secondary Hair Follicles, Oxidative Stress and Antioxidant Parameters in Cashmere Goats

5 citations , April 2024 in “Animals”

Younger cashmere goats produce more and better-quality fiber due to higher active hair follicles and antioxidant capacity.

research Comparison of the response of secondary hair follicles of cashmere and angora goats to prolactin and melatonin in vitro

1 citations , March 1994 in “Proceedings of the British Society of Animal Production”

Prolactin and melatonin affect the growth of Angora and Cashmere goat hair differently.

research Quercetin Promotes Production of Secondary Hair Follicle Stem Cells in Cashmere Goat: A Mechanistic Study

August 2025

Quercetin can boost hair follicle stem cell growth in cashmere goats, potentially improving cashmere quality.

Melatonin Promotes Secondary Hair Follicle Development in Early Postnatal Cashmere Goats and Improves Cashmere Quantity and Quality by Enhancing Antioxidant Capacity and Suppressing Apoptosis

research Melatonin promotes secondary hair follicle development of early postnatal cashmere goat and improves cashmere quantity and quality by enhancing antioxidant capacity and suppressing apoptosis

46 citations , March 2019 in “Journal of Pineal Research”

Melatonin improves cashmere goat hair growth and quality by increasing antioxidants and reducing cell death.

research Epigenetic and transcriptional profiling of secondary hair follicle stem cells during cashmere growth

March 2026 in “Scientific Data”

Chromatin state changes in hair follicle stem cells can improve cashmere growth.

research Data Sheet 2_Quercetin promotes production of secondary hair follicle stem cells in cashmere goat: a mechanistic study.zip

October 2025 in “OPAL (Open@LaTrobe) (La Trobe University)”

Quercetin boosts hair follicle stem cell growth and reduces cell death in cashmere goats.

research The cause of primary and secondary damage to hair follicles on full thickness skin autografts

2 citations , January 1974 in “Archives of Dermatological Research”

Unknown factors significantly affect hair growth in skin grafts.

research Evaluation of melatonin and bromocryptine administration in Spanish goats

10 citations , June 2005 in “Small ruminant research”

Melatonin treatment may increase cashmere production in Spanish goats.

research Inhibition of prolactin promotes secondary skin follicle activation in cashmere goats

7 citations , March 2021 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium”

Blocking prolactin increases the activity of secondary hair follicles in cashmere goats.

Effects of Melatonin Administration to Cashmere Goats on Cashmere Production and Hair Follicle Characteristics in Two Consecutive Cashmere Growth Cycles

research Effects of melatonin administration to cashmere goats on cashmere production and hair follicle characteristics in two consecutive cashmere growth cycles

8 citations , August 2020 in “Domestic Animal Endocrinology”

Melatonin improved cashmere production in goats during the first cycle but had no lasting effects on the next cycle.

NF-κB Participates in Mouse Hair Cycle Control and Plays Distinct Roles in Various Pelage Hair Follicle Types

research NF-κB Participates in Mouse Hair Cycle Control and Plays Distinct Roles in the Various Pelage Hair Follicle Types

23 citations , September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

NF-κB is crucial for different stages and types of hair growth in mice.

research Improved fetal hair follicle development by maternal supplement of selenium at nano size (Nano-Se)

18 citations , September 2011 in “Livestock science”

Maternal Nano-Se supplements improve fetal hair follicle development in cashmere goats.

research Effects of melatonin administration to cashmere goats on cashmere production and hair follicle characteristics in two consecutive cashmere growth cycles

April 2020 in “Research Square (Research Square)”

Melatonin treatment improved cashmere production in goats for one cycle without lasting effects on the next cycle.

research Melatonin Regulates the Periodic Growth of Cashmere by Upregulating the Expression of Wnt10b and β-catenin in Inner Mongolia Cashmere Goats

9 citations , July 2021 in “Frontiers in genetics”

Melatonin makes cashmere grow earlier and more by increasing certain gene activity in goats.

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Research

research Effect of Body Weight Gain During Cashmere Non-Growing Period on Cashmere Production Performance and Secondary Hair Follicle Activity of Cashmere Goats

research Effect of Fasted Live-Weight Gain during the Cashmere Non-Growing Period on Cashmere Production Performance and Secondary Hair Follicle Activity of Cashmere Goats

research Fibroblast growth factor 5-short (FGF5s) inhibits the activity of FGF5 in primary and secondary hair follicle dermal papilla cells of cashmere goats

research The influence of biotin on viability, pyruvate carboxylase activity and the response to malate concentration in vitro by isolated secondary hair follicles of the Angora goat

research Effects of photoperiod on nutrient digestibility, hair follicle activity and cashmere quality in Inner Mongolia white cashmere goats

research Seasonal variation in hair follicle activity and fibre growth of both male and female Merghoz goats in Western Iran

research Mitotic processes in hair follicles and the morphostructure of sheep skin upon inclusion of a water-soluble fatty acid complex into their diets

research Determination of Secondary Follicle Characteristics, Density, Activity, and Hoxc13 Expression Pattern of Hexi Cashmere Goats Breed

research Increasing GSH-Px Activity and Activating Wnt Pathway Promote Fine Wool Growth in FGF5-Edited Sheep

research Seasonal Gene Expression Profile Responsible For Hair Follicle Development In Angora Goats

research Effects of photoperiod change on serum hormone level, hair follicle growth and antioxidant status in skin tissue of cashmere goats

research Growth and viability of Liaoning Cashmere goat hair follicles during the annual hair follicle cycle

research Age-Related Variations in the Population of Active Secondary Hair Follicles, Oxidative Stress and Antioxidant Parameters in Cashmere Goats

research Age-Related Variations in the Population of Active Secondary Hair Follicles, Oxidative Stress and Antioxidant Parameters in Cashmere Goats

research Comparison of the response of secondary hair follicles of cashmere and angora goats to prolactin and melatonin in vitro

research Quercetin Promotes Production of Secondary Hair Follicle Stem Cells in Cashmere Goat: A Mechanistic Study

research Melatonin promotes secondary hair follicle development of early postnatal cashmere goat and improves cashmere quantity and quality by enhancing antioxidant capacity and suppressing apoptosis

research Epigenetic and transcriptional profiling of secondary hair follicle stem cells during cashmere growth

research Data Sheet 2_Quercetin promotes production of secondary hair follicle stem cells in cashmere goat: a mechanistic study.zip

research The cause of primary and secondary damage to hair follicles on full thickness skin autografts

research Evaluation of melatonin and bromocryptine administration in Spanish goats

research Inhibition of prolactin promotes secondary skin follicle activation in cashmere goats

research Effects of melatonin administration to cashmere goats on cashmere production and hair follicle characteristics in two consecutive cashmere growth cycles

research NF-κB Participates in Mouse Hair Cycle Control and Plays Distinct Roles in the Various Pelage Hair Follicle Types

research Improved fetal hair follicle development by maternal supplement of selenium at nano size (Nano-Se)

research Effects of melatonin administration to cashmere goats on cashmere production and hair follicle characteristics in two consecutive cashmere growth cycles

research Melatonin Regulates the Periodic Growth of Cashmere by Upregulating the Expression of Wnt10b and β-catenin in Inner Mongolia Cashmere Goats

research Effect of the FA2H Gene on cashmere fineness of Jiangnan cashmere goats based on transcriptome sequencing

research Towards new aspects of melatonin research in dermato‐endocrinology

research Melatonin promotes proliferation of Inner Mongolia cashmere goat hair follicle papilla cells through Wnt10b