18 citations
,
January 1992 in “The Journal of emergency medicine” Minoxidil overdose caused heart changes, treated with stomach wash, charcoal, and IV fluids.
13 citations
,
December 2010 in “Nature Reviews Endocrinology” A young man with an eating disorder had a life-threatening adrenal crisis due to an autoimmune condition, highlighting the need for better education on managing hormone treatments.
11 citations
,
October 1980 in “Archives of Dermatology” Beau's lines and hair loss in a patient were linked to severe stress on the body.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” The study concluded that a 'Swiss cheese' pattern in hair follicles is a useful sign for diagnosing alopecia areata.
October 2010 in “Journal of Men's Health” Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.
October 2010 in “Journal of Men's Health” Larger prostate size in older men may be linked to poorer semen quality and fertility issues.
April 2010 in “The Journal of Urology” Human prostate cells produce more WISP1/CCN4 when there's not enough oxygen.
March 2010 in “The Journal of Urology” Hair loss, prostate size, and urinary issues are related due to androgen effects.
63 citations
,
September 1987 in “Journal of Biological Chemistry” Minoxidil slows fibroblast growth and collagen production, potentially treating keloids, hypertrophic scars, and connective tissue disorders.
34 citations
,
November 1987 in “Archives of Dermatology” Oral minoxidil helps hair regrowth in 80% of alopecia patients, but only 18% see cosmetic improvement.
76 citations
,
May 2007 in “Menopause International” After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.
62 citations
,
December 2013 in “Aaps Journal” Squarticles effectively deliver hair growth drugs to follicles and dermal papilla cells.
54 citations
,
February 2010 in “British Journal of Dermatology” Hair loss in women may have causes other than hormones.
51 citations
,
October 1980 in “The New England Journal of Medicine” Minoxidil lowers blood pressure effectively but may cause unwanted hair growth and other side effects.
50 citations
,
September 1975 in “American Heart Journal” Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.
44 citations
,
January 2002 in “American Journal of Clinical Dermatology” Skin reactions to antidepressants are common but usually not serious and can be treated.
39 citations
,
September 2000 in “Obstetrics and Gynecology Clinics of North America” Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.
37 citations
,
April 1979 in “The Journal of Clinical Pharmacology” Minoxidil effectively controls blood pressure but side effects may limit its use.
35 citations
,
November 2010 in “Journal of Cutaneous Pathology” Dilated follicular infundibula and increased catagen/telogen follicles are key indicators for diagnosing alopecia areata.
33 citations
,
October 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride reduces hair growth and is safe for women with excessive hair.
30 citations
,
January 2014 in “Dermatologic Clinics” Tight hairstyles, especially on chemically treated hair, can cause reversible hair loss if caught early but may become permanent if not addressed.
30 citations
,
July 2001 in “BJUI” Combination therapy improves urinary flow and reduces residual urine, but needs better stent design.
29 citations
,
January 2006 in “Clinical chemistry and laboratory medicine” SHBG binding properties are unchanged in male liver cirrhosis patients.
28 citations
,
February 2010 in “British journal of dermatology/British journal of dermatology, Supplement” WNT10A mutations cause varied symptoms in patients with odonto-onycho-dermal dysplasia.
28 citations
,
January 2003 in “Skin pharmacology and physiology” Melatonin affects skin cell growth differently based on how much and how long it's used.
26 citations
,
March 2014 in “Arquivos Brasileiros De Endocrinologia E Metabologia” The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.
26 citations
,
October 1978 in “JAMA” Minoxidil helps treat severe high blood pressure.
24 citations
,
October 2008 in “International Braz J Urol” Lovastatin doesn't improve lower urinary tract symptoms treatment.
23 citations
,
July 1993 in “Pharmacotherapy” Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
23 citations
,
October 1971 in “BMJ” Stopping the pill and giving birth both caused hair loss.