April 2026 in “C&EN Global Enterprise” Serotonin's role in mental health is complex and not fully understood, affecting treatment effectiveness.
13 citations
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December 2017 in “CNS Neuroscience & Therapeutics” Finasteride affects young male rats' brain function and behavior negatively.
February 2025 in “Ciencia Latina Revista Científica Multidisciplinar” Finasteride can help with hair loss and prostate issues but may negatively affect mood and the nervous system.
11 citations
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August 2015 in “PLOS ONE” Finasteride affects brain stress and enzyme activity differently in various regions, possibly helping with liver-related brain issues.
February 2025 in “Iranian journal of pharmaceutical research” 59 citations
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March 2003 in “The Lancet” Imatinib can repigment grey hair, while SU11428 can cause temporary hair depigmentation.
November 2005 in “PubMed” 306 citations
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August 2011 in “Journal of cachexia, sarcopenia and muscle” Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.
January 2023 in “Rasayan journal of chemistry/Rasayan journal of Chemistry” Methyl pyropheophorbide A from Sansevieria trifasciata leaves may help treat hair loss.
1 citations
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May 2015 in “Journal of The American Academy of Dermatology” Finasteride for hair loss in young men may significantly increase the risk of sexual dysfunction.
May 2015 in “Journal of The American Academy of Dermatology” Finasteride for hair loss in young men increases the risk of sexual dysfunction.
52 citations
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May 2011 in “Journal of Neuroendocrinology” PEA boosts allopregnanolone production and reduces oxidative stress in brain cells.
April 2021 in “Reactions Weekly” Finasteride increases risk of depression, possibly suicidal thoughts, and sexual dysfunction.
62 citations
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January 2009 in “Epilepsia” Neurosteroid production in the brain may delay seizure onset.
June 2021 in “Reactions Weekly” Finasteride caused serious side effects and led to six suicides.
January 2026 in “Pharmaceutical journal/The pharmaceutical journal” Finasteride and dutasteride now have stronger warnings for psychiatric and sexual side effects.
May 2024 in “Reactions weekly” December 2022 in “JAMA network open” 5α-Reductase inhibitors may increase depression risk but not dementia or suicide.
September 2024 in “Frontiers in Neuroendocrinology” 5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.
October 2025 in “Scientific Reports” Serenoa repens extract shows promise as a natural treatment for prostate cancer.
1 citations
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June 2019 in “Current Developments in Nutrition” S-equol supplements significantly reduced menopausal symptoms in most women.
29 citations
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October 2009 in “Pharmacology Biochemistry and Behavior”
65 citations
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October 2008 in “Journal of Neuroendocrinology” Dutasteride may become the top choice for treating hair loss.
118 citations
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July 2005 in “Journal of Ethnopharmacology” Eclipta alba extract improved learning, memory, and stress-related ulcers in rats without affecting movement or causing anxiety.
September 2025 in “The Journal of Clinical Psychiatry” Finasteride may increase depression and suicide risks, needing better safety checks and informed consent.
February 2024 in “Urology” Certain medications, especially Paroxetine, Tamsulosin, and Finasteride, are linked to ejaculatory disorders.
Cialis and Finasteride could be repurposed to treat aggressive melanoma.
1 citations
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January 2021 in “European Journal of Inflammation” Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.
November 2023 in “Magna Scientia Advanced Research and Reviews” Trazodone might help reverse post finasteride syndrome.