115 citations
,
December 1996 in “PubMed” The safe daily selenium intake is up to 819 micrograms.
June 1998 in “Pathophysiology” Selenium is crucial for health, but both deficiency and excess can cause problems.
71 citations
,
June 2008 in “Annals of Internal Medicine” Excessive selenium from supplements can be harmful.
8 citations
,
December 2021 in “BMJ neurology open” Sodium selenate was found to be safe and possibly slows Alzheimer's progression, but more research is needed.
January 2018 in “ScholarWorks @UVM (University of Vermont)” Selenium in proteins helps prevent over-oxidation and supports chemical reversibility.
3 citations
,
January 1995 in “PubMed” Selenium therapy improved health in cystic fibrosis patients with fewer side effects at a lower dose.
February 2023 in “European journal of geriatrics and gerontology” Selenium helps prevent thyroid issues and cognitive decline in the elderly, but balance is key.
January 2013 in “University Libraries (University of Maryland)” Selenium helps protect cells from aging and damage, especially under stress.
1 citations
,
December 2019 Selenium is essential for health, but too much or too little can cause problems; blood selenium levels are a good measure of intake.
October 2009 in “The American Journal of Gastroenterology” Excessive selenium intake can cause liver damage.
101 citations
,
August 2010 in “PLoS ONE” Selenoproteins are crucial for healthy skin and hair.
1 citations
,
March 2020 in “̒Ulūm-i dārūyī” Selenium supplements improved liver and kidney function and reduced hair loss in beta-thalassemia major patients.
3 citations
,
July 2005 in “DOAJ (DOAJ: Directory of Open Access Journals)” Selenosis in calves causes health issues and changes in blood parameters.
6 citations
,
January 2005 Selenosis in calves causes health issues and changes in blood parameters.
4 citations
,
January 1989 Hair and nails can indicate selenium levels in the body.
January 1996 in “Human Ecology Forum” Selenium is important for health but must be consumed in the right amount to avoid health issues.
241 citations
,
January 2001 in “Reviews on Environmental Health” High selenium exposure can harm thyroid function, immune system, liver, skin, and may increase neurotoxicity and cancer risk.
126 citations
,
November 1987 in “The Journal of Pediatrics” Selenium deficiency can cause skin and hair color loss, muscle weakness, and blood cell changes, but these improve with selenium supplements.
382 citations
,
February 2010 in “Archives of Internal Medicine” A manufacturing error in a dietary supplement caused severe selenium poisoning, affecting many people and highlighting the need for stricter quality control.
11 citations
,
January 2016 in “BMC veterinary research” Urinary Se to creatinine ratio, serum Se, and glutathione peroxidase are effective early biomarkers for selenium status in dogs.
61 citations
,
May 2010 in “Integrative Cancer Therapies” There is no clear recommendation for using selenium in cancer patients; it may be beneficial to correct low selenium levels before treatment.
22 citations
,
August 2019 in “Environmental research” Pseudomonas sp. T5-6-I bacteria increase selenium uptake in Brassica oleracea plants by 130%.
1 citations
,
June 2009 in “Integrated Environmental Assessment and Management” Selenium is essential in small amounts but toxic in excess, requiring careful management.
November 2011 in “InTech eBooks” Selenium shows promise in preventing and controlling prostate cancer.
January 2021 in “Agrobiological records” Biofortifying fruits and vegetables with selenium can improve dietary intake and prevent health issues.
April 2017 in “The FASEB journal” Low selenium levels worsen health but increase lifespan in mice.
April 2018 in “Journal of Investigative Dermatology” Resveratrol activates the Nrf2 pathway in human skin, significantly increasing the production and distribution of the antioxidant glutathione.
44 citations
,
January 1984 in “Molecular and Cellular Biochemistry”
36 citations
,
January 2010 in “Human & experimental toxicology” Eating paradise nuts led to selenium poisoning, causing nausea, hair loss, and other symptoms in two women.