research Smart Microneedles for Therapy and Diagnosis
Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.
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research Satoyoshi syndrome: A rare multisystemic disorder requiring systemic and symptomatic treatment
A patient with Satoyoshi syndrome improved with a treatment combining several medications, including carbamazepine and methotrexate.
research Abstract 2962: Chemotherapy induced senescence drives peripheral neuropathy
Eliminating senescent cells can prevent and reverse chemotherapy-induced peripheral neuropathy.
research Topical Inhibition of the Electron Transport Chain Can Stimulate the Hair Cycle
Applying certain inhibitors to the skin can promote hair growth without harming cells.
research Recent Insights into the Potential and Challenges of Sericin as a Drug Delivery Platform for Multiple Biomedical Applications
Sericin from silk cocoons could be a promising drug delivery tool, but stability and consistency need improvement.
research Percutaneous drug delivery to the hair follicle
Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.
research Unlocking Hair Follicles as Drug Reservoirs: Advances in Transfollicular Drug Delivery
Hair follicles can be used to deliver drugs effectively, especially using nanoparticles, for treating skin conditions.
research Topical use of systemic drugs in dermatology: A comprehensive review
Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.
research Self-microemulsifying systems of Finasteride with enhanced oral bioavailability: multivariate statistical evaluation, characterization, spray-drying and in vivo studies in human volunteers
Improved Finasteride delivery for hair loss treatment.
research Organoid‐Guided Precision Medicine: From Bench to Bedside
Organoid technology is improving personalized medicine by better predicting drug responses and treatments.
research Thiopurines: Recent Topics and Their Role in the Treatment of Inflammatory Bowel Diseases
Thiopurines help treat IBD but require genetic testing to avoid side effects.
research Peripheral Neuroprotective and Immunomodulatory Effects of 5α-Reductase Inhibitors in Parkinson’s Disease Models
Dutasteride may help protect neurons and reduce inflammation in Parkinson's disease.
research Alopecia Universalis in an Elderly Chinese Man Induced by Sacubitril/Alisartan, a Novel Angiotensin Receptor-Neprilysin Inhibitor
An elderly Chinese man lost all his hair after taking a new heart medication.
research Nutraceuticals Known to Promote Hair Growth Do not Interfere with the Inhibitory Action of Tamoxifen in MCF7, T47D and BT483 Breast Cancer Cell Lines
Hair growth-promoting nutraceuticals do not block the cancer-fighting effects of tamoxifen and may enhance its action.
research Medications Most Commonly Associated With Erectile Dysfunction: Evaluation of the Food and Drug Administration National Pharmacovigilance Database
Certain medications, especially 5-α reductase inhibitors and neuropsychiatric drugs, are often linked to erectile dysfunction.
research TOPICAL STEROIDS
Use mild topical steroids to avoid side effects, especially in children.
research Nano-PROTACs: state of the art and perspectives
Nano-PROTACs could improve drug targeting and delivery by using nanotechnology.
research Advances in Research of Hydrogel Microneedle-Based Delivery Systems for Disease Treatment
Hydrogel microneedles offer a promising, minimally invasive way to treat diseases like cancer and hair loss, but need improvements in strength and standardization.
research Network-Based Approaches Reveal Potential Therapeutic Targets for Host-Directed Antileishmanial Therapy Driving Drug Repurposing
Researchers identified five new potential targets for leishmaniasis treatment, suggesting repurposing existing drugs could be effective.
research Bioconversion, Pharmacokinetics, and Therapeutic Mechanisms of Ginsenoside Compound K and Its Analogues for Treating Metabolic Diseases
Ginsenoside compound K shows promise for treating metabolic diseases like diabetes and obesity.
research Formononetin: A Pathway to Protect Neurons
Formononetin may help protect the brain and treat neurological diseases.
research Advances in nucleoside monophosphate prodrugs as anti-HCV agents
New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.
research Gender Differences in Skin Aging and the Changing Profile of the Sex Hormones with Age
The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.
research Antiepileptogenic effects of trilostane in the kainic acid model of temporal lobe epilepsy
Trilostane may help delay epilepsy development by increasing certain brain chemicals.
research Molecular interactions of progesterone derivatives with 5α-reductase types 1 and 2 and androgen receptors
Certain progesterone derivatives can inhibit enzymes and reduce androgenic activity, potentially affecting prostate growth.
research Enhanced Sensitivity to Ethanol-Induced Inhibition of LTP in CA1 Pyramidal Neurons of Socially Isolated C57BL/6J Mice: Role of Neurosteroids
Social isolation makes mice more sensitive to alcohol's effects on brain function.
research Preparation and Evaluation of Self-emulsifying Drug Delivery System (SEDDS) of Cepharanthine
research Drugs targeting epithelial–mesenchymal transition molecules for treatment of lichen planopilaris
Drugs targeting EMT molecules show promise for treating lichen planopilaris.
research The biology and clinical application of systemic glucocorticoids
Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.
research Solid Lipid Nanoparticles for Drug Delivery: Pharmacological and Biopharmaceutical Aspects
Solid lipid nanoparticles are promising for safe and effective drug delivery but need more research for clinical use.