January 2008 in “Journal of The American Academy of Dermatology” Hair loss affects 20% of people, more in men and those over 35, and is often associated with a sensitive scalp.
May 2018 in “Endocrine Abstracts” SFRP-4 might be an early indicator of diabetes and hypertension in men with androgenic alopecia.
4 citations
,
March 1991 in “Dermatitis” Minoxidil can cause skin reactions, so testing is important for those with side effects.
232 citations
,
January 2016 in “BMC Bioinformatics” The method can effectively extract biomedical information without needing expert annotation, performing better than previous models.
137 citations
,
January 2000 in “Skin Pharmacology and Physiology” The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.
124 citations
,
April 1992 in “Journal of Endocrinology/Journal of endocrinology” Beard hair follicles have more androgen receptors than non-balding scalp hair follicles.
83 citations
,
October 2012 in “International Journal of Oncology” Wedelolactone selectively kills prostate cancer cells without harming normal cells.
73 citations
,
November 2001 in “Journal of Investigative Dermatology Symposium Proceedings” Markers help differentiate between apocrine and eccrine sweat glands to identify sweat gland tumors.
53 citations
,
February 2020 in “Expert Opinion on Pharmacotherapy” Finasteride and minoxidil work best together for hair loss.
50 citations
,
May 2019 in “BioFactors” Pollution increases a compound in the skin that can lead to faster aging and more inflammation.
47 citations
,
October 1989 in “Circulation Research” The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.
46 citations
,
May 1997 in “British journal of dermatology/British journal of dermatology, Supplement” Vitiligo is not linked to coeliac disease, but a small number of alopecia areata patients may have it, suggesting they should be tested for coeliac disease.
44 citations
,
January 2007 in “Biological & pharmaceutical bulletin” Black pepper leaf extract contains compounds that can block testosterone effects and promote hair growth.
36 citations
,
October 2009 in “Journal of Investigative Dermatology” Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.
33 citations
,
May 1991 in “British Journal of Pharmacology” Cromakalim relaxes various blood vessels, while minoxidil sulphate is more selective; they likely act on different potassium channels.
32 citations
,
September 1989 in “Medical Clinics of North America” Skin problems are common in lupus, important for diagnosis, and can be triggered by sunlight.
31 citations
,
April 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.
30 citations
,
April 2009 in “Dermatologic Surgery” TrichoScan helps identify subtle hair thinning in women with androgenetic alopecia.
30 citations
,
June 1988 in “Journal of Steroid Biochemistry” Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.
29 citations
,
April 2017 in “Macromolecular bioscience” Scientists created tiny pH-sensing gels that can safely measure the pH levels inside hair follicles.
25 citations
,
December 2017 in “The Journal of Clinical Endocrinology & Metabolism” Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.
24 citations
,
April 2014 in “Oncotarget” Minoxidil can reduce functions related to androgen receptors.
21 citations
,
December 2014 in “Clinics in dermatology” Squaric acid dibutylester effectively treats alopecia areata.
19 citations
,
October 2017 in “European Journal of Pharmaceutics and Biopharmaceutics” The gel made of minoxidil and hydroxypropyl-β-cyclodextrin improves hair growth and is good for long-term use.
18 citations
,
October 2020 in “Journal of Pharmacology and Experimental Therapeutics” KATP channel openers may cause peripheral edema by reducing lymphatic contractions and flow.
18 citations
,
February 2014 in “PubMed” Androgenetic alopecia is a common hair loss condition caused by testosterone effects on hair follicles, leading to thinner, shorter, and less pigmented hair, diagnosed using scalp dermoscopy and treated with topical minoxidil, antiandrogen agents, and 5-alpha reductase inhibitors.
17 citations
,
December 2020 in “Journal of Genetic Counseling” Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.
17 citations
,
August 2012 in “Archives of Pharmacal Research” Acankoreoside J from Acanthopanax koreanum may help promote hair growth.
14 citations
,
September 1986 in “Archives of Dermatology” Women with low SHBG levels and a high 3a-diol G to SHBG ratio are likely to experience female pattern baldness, possibly due to a slight excess of androgens affecting sensitive hair bulbs.
12 citations
,
May 2021 in “Clinical Interventions in Aging” Men with androgenetic alopecia have oilier and less hydrated scalps, especially in sensitive areas.