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Alopecia areata involves immune system changes, especially in severe cases, with potential new treatment targets identified.

Certain microRNAs may help treat alopecia areata by targeting immune pathways.

Nonimmunosuppressive cyclosporines might treat skin diseases by affecting cell growth.

Current corticosteroid pulse therapy is not very effective for severe rapidly progressive alopecia areata.

JAK inhibitors may help treat alopecia areata by reversing hair loss.

The study found that a one-step antibody method is better than the LSAB method for accurately studying hair follicle structures without false positives.

Dupilumab may help treat alopecia areata without needing high IgE levels.

Cells that move well may improve hair loss treatments by entering hair follicles.

Cutaneous lupus patients have higher levels of certain immune cells in their blood and skin.

Janus kinase inhibitors are the most supported treatment for pediatric alopecia areata, while other options have limited evidence.