July 2025 in “Saudi Journal of Medicine and Public Health” 5α-reductase inhibitors effectively treat enlarged prostate and hair loss but require careful use due to possible side effects.
18 citations
,
May 2020 in “Biomolecules” Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
29 citations
,
June 2018 in “Scientific Reports” 15-lipoxygenase helps keep skin healthy by reducing inflammation.
Isotretinoin effectively improved severe pityriasis rubra pilaris with complications.
12 citations
,
January 2012 in “Dermatology” Finasteride helped treat a 28-year-old's facial skin condition.
August 2024 in “Latin American Journal of Development” 5α-reductase enzymes are crucial in certain disorders, and while treatment advances exist, more research on SRD5A3 is needed.
3 citations
,
January 2018 A woman had an unusual allergic reaction to a hair loss treatment, which cleared up after stopping the treatment and using a different medication.
August 1986 in “Journal of The American Academy of Dermatology” Minoxidil showed a 30% success rate for hair growth in a study, and various skin treatments were effective, but some had limitations or side effects.
38 citations
,
October 1996 in “Dermatologic Clinics” Certain hormone treatments can improve acne and related conditions in women.
10 citations
,
August 1998 in “Journal of Investigative Dermatology” The compounds tested could potentially treat hair loss and alopecia.
September 2025 in “Reactions Weekly”
19 citations
,
January 1987 in “Dermatology” Minoxidil slows down skin cell growth and may help treat scars and skin conditions.
12 citations
,
January 2018 in “Journal of Drug Delivery Science and Technology” The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.
March 2006 in “مجله علوم پزشکی رازی” Prednisone may regrow hair in some alopecia areata patients, but has side effects; minoxidil can help limit hair loss.
April 2023 in “Journal of Drug Delivery Science and Technology” The new minoxidil gel improves hair growth and reduces skin irritation.
219 citations
,
October 2009 in “Steroids” 5α-reductase inhibitors, like Finasteride and Dutasteride, help manage benign prostatic hyperplasia.
8 citations
,
March 2002 in “Archiv Der Pharmazie” The compound 4c effectively inhibits the enzyme linked to hair loss.
May 2021 in “The FASEB Journal” The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.
2 citations
,
October 2016 in “European Neuropsychopharmacology”
6 citations
,
February 2016 in “Journal of Microencapsulation” Improved finasteride formula allows slow, sustained release and better absorption for patients.
January 2017 in “Nutrafoods - International Journal on Nutraceuticals, Functional Foods and Novel Foods” The supplement reduces hair loss and increases hair thickness in older women.
June 2026 in “ChemistryOpen” Modified nanofibers improve finasteride skin absorption.
August 2018 in “Cadernos de Agroecologia” The new sulfur paste effectively treats rabbit scabies, promoting healing and hair growth.
15 citations
,
May 1987 in “Fundamental and applied toxicology” SMR-2 and SMR-6 are much more toxic than retinoic acid, causing severe side effects.
January 2026 in “RSC Advances” Epristeride's metabolism in zebrafish helps improve doping detection methods.
1 citations
,
April 2024 in “Skin research and technology” Topical rosuvastatin and melatonin creams significantly reduce psoriasis severity and are safe.
Spironolactone is a promising alternative to antibiotics for treating acne in adult females.
11 citations
,
May 1996 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.
2 citations
,
January 2015 in “Journal of Investigative Dermatology” February 2019 in “Journal of Physiology & Pathology in Korean Medicine” Puerariae Radix extract may be a promising cosmetic ingredient for skin health.