January 2016 in “Archivio italiano di urologia, andrologia” The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.
January 2026 in “Figshare” Finasteride can cause melasma, especially in people with darker skin.
August 2018 in “Journal of The American Academy of Dermatology” October 2025 in “CRC Press eBooks” 
1 citations
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November 2015 in “Cochrane library” 5-alpha-reductase inhibitors help treat urinary symptoms from an enlarged prostate.
24 citations
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May 2015 in “Schizophrenia Research” A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.
July 2016 in “Reactions Weekly” Cyproterone and finasteride reduced hypersexuality but caused serious side effects.
41 citations
,
March 2010 in “Psychology Research and Behavior Management” Using psychological treatments can help manage skin conditions along with regular medical care.
60 citations
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June 2007 in “Pharmacology Biochemistry and Behavior” Blocking progesterone metabolism can cause depression-like behavior in mice.
February 2023 in “Reactions Weekly” May 2025 in “Reactions Weekly” December 2023 in “Reactions weekly” December 2023 in “Reactions weekly” September 2013 in “Reactions weekly” 
October 2017 in “The Journal of Urology” 5α-Reductase inhibitors can negatively impact sexual function.
January 2005 in “Psychoneuroendocrinology” Finasteride may affect brain chemistry and behavior, offering potential for treating certain mental health conditions.
2 citations
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November 2021 in “Journal of Clinical Psychopharmacology” Finasteride may affect mood and increase suicidal risk.
1 citations
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December 2019 in “Current Medicinal Chemistry” Anti-androgen drugs can help reduce OCD symptoms, but more large-scale trials are needed to confirm their effectiveness.
May 2023 in “The Journal of Sexual Medicine” Flibanserin may help improve sexual symptoms in various conditions beyond its approved use.
April 2011 in “Reactions Weekly” 14 citations
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June 1995 in “The Journal of Clinical Endocrinology and Metabolism” February 2026 in “Case Reports in Dermatology” Finasteride can cause melasma, especially in people with darker skin.
14 citations
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December 2007 in “Journal of The European Academy of Dermatology and Venereology” The article concludes that dermatologists should prescribe lifestyle drugs carefully and consider mental health treatments for patients with disorders like BDD.
42 citations
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December 2007 in “American Journal of Psychiatry” Finasteride may effectively reduce Tourette's syndrome symptoms and improve life quality.
February 2025 in “International Urology and Nephrology” Peripheral treatments showed some improvement in sexual dysfunction, but central symptoms remain challenging.
16 citations
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November 2018 in “Medicinal Chemistry” The compound GD-23 may reduce anxiety like diazepam by targeting the TSPO receptor.
October 2017 in “The Journal of Urology” Finasteride reduces the need for prostate surgery but may increase the risk of depression and persistent sexual side effects.
11 citations
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August 2019 in “BMJ” Post-finasteride syndrome causes sexual, physical, and psychological symptoms, but more research is needed to understand its causes and connection to finasteride.