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Finasteride can cause long-term side effects like sexual dysfunction and depression.

SRD5A2 gene variations affect PTSD symptoms differently in males and females.

Heart-specific steroid metabolism is crucial in cardiac hypertrophy.

Choose treatments for sex offenders based on individual needs, using hormonal and nonhormonal options to reduce sexual drive.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Morphine increases testosterone breakdown in the rat brain and spinal cord.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

Venlafaxine may cause paranoid delusions in some patients.

Early changes in brain chemicals affect how a drug reduces alcohol intake in rats.

Some people have a genetic variation that makes them less effective at breaking down drugs.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

5-alpha reductase inhibitors slightly increase depression risk, but the risk varies based on the control group used.

Finasteride can cause side effects, some lasting after treatment ends, and may lead to severe depression or suicidal thoughts.

5alpha-reductase 2 is crucial for proper male brain development and sexual differentiation.

Finasteride is made through a series of chemical reactions starting from a specific intermediate compound.

Ethanol withdrawal reduces the brain's response to certain calming steroids, making seizures harder to control.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

Scientists identified three genes important for processing certain brain chemicals, thyroid hormones, and medications.

Patients with acne and insulin resistance have different blood metabolites compared to those with only acne, which could help in diagnosis and treatment.

Escitalopram might effectively treat delusions of parasitosis and possibly Morgellons disease, with psychological factors being important to consider.

Finasteride may help improve certain brain function issues linked to dopamine.

Finasteride has various adverse effects, including sexual dysfunction and mental health issues, which vary by age and gender.

Finasteride for hair loss often causes depression, with risks outweighing benefits.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.