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Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Stopping finasteride improved seizure control, suggesting neurosteroids affect seizures and treatment.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.

UHP-sCESr is as effective as HESr for treating BPH symptoms.

Testosterone increases seizure risk through its conversion to specific neurosteroids.

5α-reductase inhibitors may cause persistent sexual dysfunction and depression, needing more research on long-term effects.

This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.

Finasteride may cause depression and suicidal thoughts, especially in young men.

Finasteride use may increase suicidality risk, especially in young men.

Mirtazapine may cause hair loss and change hair color, but stopping the drug can reverse these effects.

Targeting neurosteroids may help prevent drug relapse.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Progesterone and its metabolites can prevent seizures without major side effects.

Higher estrone-to-estradiol ratios are linked to worse glucose metabolism and insulin resistance in women with PCOS.

PM-9, like finasteride, may help treat certain diseases by blocking a key enzyme.

Retinoic acid affects male and female muscle energy use and function differently.

Dermatologists in Western Rajasthan often prescribe doxepin for elderly patients with skin and mental health issues.

Blocking certain brain processes reduces mating behavior in female rats.

Finasteride may increase the risk of depression, anxiety, and suicidal thoughts.

Researchers created a new method to measure brain steroids, finding higher levels of certain steroids and changes due to a drug.

SPET-085 effectively inhibits an enzyme linked to prostate issues, similar to finasteride.

Stopping alcohol after long-term use causes anxiety and changes brain chemicals.

Finasteride worsens alcohol withdrawal in female mice but eases it in male mice.

Microbes in the small intestine may cause Post-Finasteride Syndrome symptoms.

Lower allopregnanolone levels increase stress-related dopamine release in the brain.