September 2025 in “The Journal of Clinical Psychiatry” Finasteride may increase depression and suicide risks, needing better safety checks and informed consent.
27 citations
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June 2013 in “Alcoholism: Clinical and Experimental Research” Finasteride use may lead to less alcohol consumption in men with lasting sexual side effects.
36 citations
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June 2019 in “eLife” The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.
December 2025 in “Instituto Politécnico do Porto” Patients with mood disorders using 5α-reductase inhibitors may have a higher risk of suicidal thoughts.
January 2006 in “Guangzhou Chemistry” The new method for making Finasteride is cheaper and safer for large-scale production.
29 citations
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January 1996 in “Journal of Pharmaceutical Sciences” Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.
January 2016 in “SHILAP Revista de lepidopterología” Switching from escitalopram to duloxetine helped stop hair loss.
8 citations
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March 2012 in “Mass spectrometry letters” The S9 fraction with GC-IDMS is effective for measuring 5α-reductase activity.
March 2025 in “Journal of Cosmetic Dermatology” Finasteride use may increase depression and suicide risk, especially at 1 mg, so monitoring is advised.
3 citations
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April 2021 in “Journal of Medicinal Chemistry” Finasteride may affect PNMT, causing side effects.
4 citations
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May 2019 in “The World Journal of Men's Health” Taking 5 alpha reductase inhibitor medication slightly increases the risk of depression, especially as you get older.
Finasteride may affect female fertility by altering gene activity.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Microbes in the small intestine may cause Post-Finasteride Syndrome symptoms.
May 2026 in “ACS Catalysis” Efficient enzyme function relies on specific residue interactions and structural coordination.
January 2005 in “Psychoneuroendocrinology” Finasteride may affect brain chemistry and behavior, offering potential for treating certain mental health conditions.
October 2010 in “Journal of Men's Health” Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.
11 citations
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August 2019 in “BMJ” Post-finasteride syndrome causes sexual, physical, and psychological symptoms, but more research is needed to understand its causes and connection to finasteride.
The trial aims to understand how obesity and lifestyle affect circadian rhythms in people with schizophrenia and bipolar disorder.
22 citations
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April 1972 in “Journal of Steroid Biochemistry” Beard hair follicles convert testosterone to 5α-dihydrotestosterone most intensively.
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