44 citations
,
April 2008 in “The Journal of Clinical Endocrinology & Metabolism” Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.
72 citations
,
October 1998 in “Baillière's clinical endocrinology and metabolism” Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.
32 citations
,
August 1999 in “Journal of Investigative Dermatology” Early onset hair loss linked to genetics and androgen levels.
10 citations
,
May 2017 in “PLOS ONE” Men and premenopausal women in Korea show different patterns in iron and vitamin D levels, with no clear pattern for postmenopausal women.
Lower vitamin D levels are linked to more severe hair loss in men.
May 2024 in “International journal of research in dermatology” Low vitamin D levels are linked to increased risk of male pattern baldness.
11 citations
,
May 2010 in “Journal of Medicinal Chemistry” A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.
11 citations
,
March 2009 in “Bioorganic & Medicinal Chemistry Letters” Chemicals called 4-(alkylthio)- and 4-(arylthio)-benzonitrile derivatives can potentially reduce oil production on skin, which could help treat conditions like acne and hair loss.
11 citations
,
August 2007 in “Bioorganic & Medicinal Chemistry Letters” Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.
7 citations
,
April 2009 in “Bioorganic & Medicinal Chemistry Letters” Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.
5 citations
,
September 2011 in “Bioorganic & Medicinal Chemistry Letters” Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
38 citations
,
February 2005 in “The journal of sexual medicine” The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.
10 citations
,
April 2006 in “Seminars in Reproductive Medicine” Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.
February 2018 in “The Journal of Sexual Medicine” Natesto nasal gel improves erectile function and mood in men with low testosterone within 30 days.
7 citations
,
April 2012 in “Clinical investigation” Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.
31 citations
,
October 2005 in “British Journal of Dermatology” Hair loss in women not always linked to increased oil production; other factors may be involved.
12 citations
,
January 2020 in “touchREVIEWS in Endocrinology” Testosterone may both worsen and protect against COVID-19 effects in men.
2 citations
,
September 2007 in “International Journal of Impotence Research” Local testosterone treatment improved sexual desire in a female with fragile X syndrome.
July 2020 in “International Journal of Research” High testosterone increases heart disease risk in women with PCOS.
March 2004 in “Current Sexual Health Reports” Testosterone's role in women's sex drive is unclear and needs more research, as low levels don't always mean less sexual interest and high levels can cause side effects.
July 2021 in “Archives of Dermatological Research” Alopecia patients have less GPER-1, which might affect hair loss.
255 citations
,
October 1985 in “The Journal of Clinical Endocrinology & Metabolism” Spironolactone treatment increases the amount of testosterone available in the body.
8 citations
,
February 2009 in “Current Women's Health Reviews” Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.
71 citations
,
January 2014 in “Journal of Proteome Research” Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.
37 citations
,
March 2014 in “Journal of Trace Elements in Medicine and Biology” Lower hair zinc and copper levels found in Turkish males with hair loss; higher BMI linked to less hair zinc.
33 citations
,
January 1997 in “Endocrinology” Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.
18 citations
,
September 2015 in “Clinical Endocrinology” Women with PCOS have higher levels of a certain growth factor, which can be reduced by taking metformin.
17 citations
,
January 1997 in “Cell and Tissue Research” Scientists developed a method to grow human fetal skin and digits in a lab for 3-4 weeks, which could help study skin features and understand genetic interactions in tissue formation.
16 citations
,
August 2007 in “Histopathology” A woman's rare adrenal tumor caused high testosterone and cortisol levels, which normalized after the tumor was removed.
14 citations
,
September 2020 in “Clinical, cosmetic and investigational dermatology” The hair serum significantly improved hair growth and reduced hair fall without causing any skin issues.