158 citations
,
August 2011 in “Reviews in endocrine and metabolic disorders” Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.
57 citations
,
April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D receptor is crucial for starting hair growth after birth.
50 citations
,
October 1986 in “European journal of pediatrics” A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.
31 citations
,
January 2007 in “Journal of biological chemistry/The Journal of biological chemistry” Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.
28 citations
,
January 2012 in “Biological & pharmaceutical bulletin” Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.
18 citations
,
September 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” VDUP1 is found in skin and hair follicles, interacts with sciellin, and may help regulate skin cell differentiation.
10 citations
,
February 2008 in “Photochemistry and photobiology” Vitamin D receptor can control the hairless gene linked to hair loss even without vitamin D.
April 2025 in “Egyptian journal of Immunology” Calprotectin levels are higher in alopecia areata patients, indicating systemic inflammation.
3 citations
,
January 2016 in “Annals of Dermatology” Vitamin D may help reduce inflammation in acne.
4 citations
,
March 2018 in “PloS one” Men with less sun-sensitive skin have lower PSA levels, while men with more sun-sensitive skin have higher PSA levels.
July 2012 in “British Journal of Dermatology” Hair loss treatments show limited improvement, sunscreen thickness affects vitamin D production, and the effectiveness of IVIg for toxic epidermal necrolysis is uncertain.
September 2025 in “International Journal for Research in Applied Science and Engineering Technology” Guava leaf extracts are beneficial for skin, hair, and oral care.
December 2025 in “Cureus” Higher IL-17A and IL-23 levels are linked to alopecia areata severity and could help in tracking and treating the disease.
October 2019 in “Turkderm” Patients with pernio have lower vitamin B12 and ferritin levels than healthy people.
1 citations
,
October 2024 in “FARMACIA” Low levels of zinc and selenium in the body are linked to a higher risk of cataracts.
October 2023 in “Benha Journal of Applied Sciences” Methotrexate and vitamin D3 are potentially more effective and safer than triamcinolone for treating localized alopecia areata.
April 2026 in “Al-Kufa University Journal for Biology” Finasteride lowers cortisol and raises testosterone levels in rats.
21 citations
,
June 2011 in “Journal of child neurology” Valproic acid and carbamazepine do not change biotin or biotinidase levels but may lower zinc levels, still within normal range.
January 2018 in “Trace Elements in Medicine (Moscow)” Children with autism have different levels of certain metals and elements in their hair and blood, affecting symptoms.
7 citations
,
May 2024 in “Life” Younger people may have a higher risk of hair loss due to poor nutrition and lifestyle.
54 citations
,
June 2001 in “The Indian Journal of Pediatrics” Lower hair zinc levels may be linked to Neural Tube Defects.
417 citations
,
February 2004 in “The Journal of Clinical Endocrinology and Metabolism” Testosterone therapy increases bone density in older men with low testosterone levels.
6 citations
,
June 2018 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” Patients with the same genetic mutation for vitamin D-resistant rickets showed different symptoms but all improved with treatment except for hair loss.
33 citations
,
September 2014 in “Reproductive Biology and Endocrinology” High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.
25 citations
,
August 2014 in “Endocrinology” Researchers created a mouse model of a type of rickets that does not cause hair loss.
11 citations
,
June 1996 in “Nutrition” Vitamin D3 may prevent hair loss from chemotherapy, but side effects and cancer cell protection are concerns.
January 2024 in “Biomedical journal of scientific & technical research” Vitamins A, B7, C, D, and E are essential for healthy hair growth and preventing damage.
January 2024 in “Biological trace element research” Isotretinoin affects trace element levels and requires monitoring of liver and kidney functions.
9 citations
,
November 2014 in “Journal of Cutaneous Medicine and Surgery” Many dermatologists in Saudi Arabia recommend vitamins and minerals for hair loss, often based on personal experience rather than strong evidence.
10 citations
,
October 1993 in “Archives of dermatological research” Vitamin D compounds may help treat psoriasis by promoting skin cell differentiation.