May 2025 in “JEADV Clinical Practice” Tofacitinib and methotrexate successfully treated a woman's severe skin, joint, and hair loss issues.
New drugs, baricitinib and ritlecitinib, are effective for severe alopecia areata.
September 2020 in “Benha Journal of Applied Sciences” Higher IL-19 levels are linked to more severe Alopecia Areata.
December 2025 in “Chinese Medical Journal” Experts recommend starting systemic treatment for alopecia areata when the condition is severe or causes significant distress.
17 citations
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June 2024 in “Journal of the European Academy of Dermatology and Venereology” Alopecia areata significantly affects mental health, especially in women and those with severe cases.
4 citations
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January 2025 in “Dermatologica Sinica” Experts recommend personalized treatment plans for alopecia areata, using corticosteroids and minoxidil for mild cases, and stronger medications for severe cases.
January 2019 in “Figshare” Intralesional corticosteroids are best for mild alopecia areata, and DPCP is best for severe cases.
2 citations
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June 1983 in “Proc., Annu. Meet., Air Pollut. Control Assoc.; (United States)” Ingesting minoxidil can cause severe health issues, requiring urgent medical treatment.
July 2023 in “Dermatology practical & conceptual” The machine learning model effectively assesses the severity of hair loss and could help dermatologists with treatment decisions.
September 2024 in “Indian Journal of Dermatology” Trichoscopy effectively diagnoses and assesses the severity of androgenetic alopecia.
3 citations
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July 2024 in “Journal of Clinical Medicine” Alopecia areata patients have a higher risk of subclinical atherosclerosis, and carotid ultrasound can help assess their cardiovascular risk.
3 citations
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April 2023 in “Dermatologica Sinica” PRP treatment may help with alopecia areata, especially in newer cases.
October 2022 in “JAAD international” Most patients with autoimmune blistering diseases experienced some hair loss, which may be underreported and linked to disease severity.
30 citations
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January 2014 in “Annals of Dermatology” Scalp dermatoscopy helps diagnose and monitor hair loss severity.
September 2025 in “International Journal of Molecular Sciences” International guidelines for treating alopecia areata vary, focusing on different treatment options and related health issues.
1 citations
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April 2020 in “Magnetic Resonance in Medical Sciences” MRI helps evaluate androgenetic alopecia severity.
25 citations
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December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” A new mouse model helps understand and find treatments for alopecia areata.
3 citations
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February 2022 in “Dermatology practical & conceptual” The study concludes that early diagnosis of Frontal Fibrosing Alopecia is important, as it is often found in postmenopausal women, may be related to Lichen Planopilaris, and eyebrow hair loss is a common sign.
March 2004 in “Journal of The American Academy of Dermatology” Minoxidil solution increases hair growth; Shampoo B best for dandruff; infliximab helps pemphigus vulgaris.
March 2022 in “Wound practice & research” New treatments for alopecia areata show promise, but standardized guidelines are needed.
1 citations
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December 2025 in “Photodermatology Photoimmunology & Photomedicine” Phototherapy effectively treats certain alopecia areata types, especially if started early.
February 2026 in “The Journal of Dermatology” Ritlecitinib effectively regrows scalp, eyebrow, and eyelash hair in Asians with alopecia areata and is safe.
89 citations
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October 1996 in “Dermatologic Clinics” Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.
21 citations
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January 2010 in “International Journal of Trichology” TrichoScan often makes mistakes and needs improvement for correct hair growth analysis.
29 citations
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January 2019 in “Journal of the European Academy of Dermatology and Venereology” Trichoscopy is useful for diagnosing and monitoring systemic lupus erythematosus, with certain hair and scalp changes indicating more active disease.
1 citations
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January 2025 in “Therapeutic Advances in Drug Safety” Antituberculosis drugs can cause severe skin reactions, requiring careful diagnosis and treatment.
1 citations
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September 2025 in “Clinical Cosmetic and Investigational Dermatology” Upadacitinib is effective and safe for treating severe Alopecia Areata in adolescents.
March 2024 in “Clinical, cosmetic and investigational dermatology” Severe alopecia areata greatly impacts quality of life, mental health, and daily activities.
39 citations
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January 2019 in “Journal of the American Academy of Dermatology” Tofacitinib may help treat severe childhood alopecia areata, but risks require careful consideration.
1 citations
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August 2019 in “Australasian journal of dermatology” Immunotherapy can help treat severe alopecia areata.