September 2021 in “International Journal of Biomedicine” Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.
January 2015 in “British journal of medicine and medical research” A woman with severe hair loss due to systemic sclerosis regrew her hair in 4 months using a combination of treatments.
July 2017 in “The American Journal of Cosmetic Surgery” A patient's hair loss after a browlift surgery improved on its own over 8 months.
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June 2018 in “The New England Journal of Medicine” A woman with Cushing's syndrome improved after surgery to remove a tumor causing the condition.
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April 1982 in “Lancet” Most patients with hard-to-treat high blood pressure can be managed effectively with various treatments, but no single treatment is perfect.
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March 2007 in “Journal of hypertension” Minoxidil effectively lowers blood pressure in patients with resistant hypertension.
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December 1980 in “The New England Journal of Medicine” Minoxidil helped bald patient regrow hair.
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January 2008 in “Annals of Dermatology” Combining Cyclosporine A with low-dose corticosteroids effectively treats severe alopecia areata.
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March 2021 in “Journal of Dermatology Research and Therapy” Women with cicatricial hair loss may have a higher risk of hypertension.
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October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
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May 2011 in “Movement Disorders” Finasteride significantly reduced tics and obsessive-compulsive symptoms in Tourette syndrome patients.
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September 2019 in “Journal of Cosmetic Dermatology” FUE megasession effectively treats severe hair loss with natural-looking results in one operation.
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October 2023 in “Dermatology and therapy” Some treatments for severe hair loss work but often have side effects, with baricitinib showing the most promise.
June 2025 in “Journal of Endocrinological Investigation” Adrenal disorders often cause high blood pressure in young people.
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February 2018 in “Journal of Investigative Dermatology” Tofacitinib may help treat severe hair loss, but more research is needed.
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November 2022 in “British journal of dermatology/British journal of dermatology, Supplement” Baricitinib for severe alopecia areata is generally safe, with common side effects like infections and acne, and low rates of serious complications.
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January 2008 in “Gynecological Endocrinology” High levels of male hormones in women without tumors are linked to metabolic problems and can be treated with metformin.
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November 2020 in “Movement Disorders Clinical Practice” A man developed neurological issues from SARS-CoV-2 without severe breathing problems, worsening to death.
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October 2024 in “Cureus” PCOS may increase the risk of high blood pressure and heart issues.
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March 2024 in “BioDrugs” Biologics for severe asthma have known side effects, but some new risks need more study.
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January 1996 in “Gynecological endocrinology” Non-invasive imaging helped diagnose a woman's severe hormone imbalance and diabetes, and medication successfully treated her condition.
The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.
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