56 citations
,
February 2006 in “American journal of physiology. Cell physiology” Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.
38 citations
,
November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” 30 citations
,
July 2023 in “Journal of Cutaneous Medicine and Surgery” Understanding sex and gender differences can improve personalized dermatology care.
23 citations
,
March 1958 in “JNCI Journal of the National Cancer Institute” Male-to-female skin grafts in mice are rejected due to sex-linked antigens.
21 citations
,
December 2015 in “Development Growth & Differentiation” DHT is crucial for urethral formation, and its disruption can affect masculinization and lead to hypospadias.
21 citations
,
November 2014 in “Journal of Endocrinological Investigation” Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.
13 citations
,
August 2016 in “Reproduction” High doses of nandrolone decanoate disrupt ovarian hormones and receptors in rats, with recovery only at lower doses and longer recovery times.
7 citations
,
September 2022 in “Communications biology” Omega-6 fats in certain cells boost male hormone production.
4 citations
,
January 2023 in “Journal of Human Hypertension” Women experience more side effects and have worse blood pressure control from hypertension treatments than men, despite using different medications.
4 citations
,
January 2021 in “The Southwest Respiratory and Critical Care Chronicles” Men and minority groups face higher risks and severe outcomes from SARS-CoV, MERS-CoV, and COVID-19.
1 citations
,
October 2025 in “Biology of Sex Differences” Gender and social factors, not just biology, affect COVID-19 death rates.
1 citations
,
July 2022 in “BMC Women s Health” An ovarian tumor can cause high male hormones in postmenopausal women.
September 2025 in “Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi” Hormonal changes in women can worsen gum disease, so dentists and gynecologists should work together for early diagnosis and treatment.
January 2025 in “Science World Journal” Male and female scalp hair differ in size, density, length, curliness, pigmentation, and cuticle preservation.
June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Male hormones and reduced plakoglobin can impair heart electrical function and increase arrhythmia risk in males.
July 2021 in “Advances in laboratory medicine” Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.
January 1986 in “Journal of Steroid Biochemistry” Lower testosterone levels in men may be linked to a higher risk of severe coronary artery disease.
185 citations
,
August 2020 in “Mayo Clinic Proceedings” Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.
110 citations
,
January 1984 in “Progress in brain research” Gonadal hormones may influence sex differences in play fighting in animals, but their effect on human spatial behavior is unclear and needs more research.
52 citations
,
March 2022 in “Biology of Sex Differences” Females have stronger immune responses to COVID-19 than males, leading to better outcomes.
34 citations
,
March 2003 in “Veterinary Dermatology” Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.
22 citations
,
August 2020 in “Journal of the American Academy of Dermatology” Women with lichen planopilaris and frontal fibrosing alopecia often have other health issues like hypothyroidism and lupus.
19 citations
,
March 1998 in “Endocrinology” Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.
13 citations
,
June 2024 in “Frontiers in Genetics” About 50% of 46, XY DSD cases lack a genetic diagnosis, but advanced sequencing methods improve detection.
10 citations
,
December 2020 in “Frontiers in Medicine” Men are more at risk for severe COVID-19 due to biological differences, suggesting the need for targeted treatments.
8 citations
,
November 2023 in “Social Science & Medicine” Gendered social factors, not just biology, contribute to sex differences in adverse drug events.
8 citations
,
July 2019 in “Journal of Molecular Neuroscience” 7 citations
,
February 1962 in “Experimental Biology and Medicine” Male and female mice have different lipid compositions in their skin during hair growth cycles.
5 citations
,
March 2024 in “Journal of Clinical Medicine” Females are more likely than males to experience long-COVID symptoms and heart issues.
4 citations
,
September 2024 in “Frontiers in Endocrinology” Serum steroid profiling, especially 11-deoxycortisol, helps distinguish between adrenocortical carcinoma and adenoma, considering sex and functional status.