50 citations
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May 2018 in “International journal of cardiology” Testosterone is linked to cardiovascular risk factors and stroke, but its exact role is unclear.
50 citations
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March 2001 in “Clinics in Dermatology” Genes and hormones cause hair loss, with four genes contributing equally.
47 citations
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September 2016 in “Reviews in endocrine and metabolic disorders” The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
46 citations
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July 1988 in “Journal of The American Academy of Dermatology” Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.
46 citations
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July 1974 in “The Journal of Clinical Endocrinology & Metabolism” Low estrogen and high testosterone may cause excessive hair growth in women.
43 citations
,
July 1984 in “Clinical and Experimental Dermatology” Antiandrogen therapy helped increase hair growth in women with hormonal imbalances related to baldness.
42 citations
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February 1985 in “Journal of the American Academy of Dermatology” Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.
41 citations
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April 2006 in “Hormone and metabolic research” Steroid-binding globulins have important roles beyond just transporting steroids.
39 citations
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August 2004 in “International journal of gynaecology and obstetrics” Finasteride and CPA-EE2 equally reduce hirsutism, but affect hormone levels differently.
39 citations
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January 2004 in “Physiological Research” Some men with early hair loss may have a condition similar to PCOS in women.
39 citations
,
November 1978 in “Annals of internal medicine” Spironolactone may help reduce excessive hair growth in women with high male hormone levels.
37 citations
,
December 2003 in “Reproductive Toxicology” The assay effectively detects hormonal activity of certain chemicals.
35 citations
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December 2009 in “Human reproduction” Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.
34 citations
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April 2023 in “Climacteric” Gender-affirming hormone therapy affects health risks and requires careful management, especially as transgender individuals age.
34 citations
,
August 2015 in “Frontiers in Behavioral Neuroscience” Allopregnanolone affects fear responses differently in male and female rats, possibly explaining sex differences in anxiety disorders.
34 citations
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November 1998 in “Journal of Investigative Dermatology” A common mutation in the hHb6 gene is linked to monilethrix, but other factors may also play a role.
33 citations
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December 2017 in “Journal of neuroendocrinology” Sex and stress steroids quickly change brain cell structures in the hippocampus.
32 citations
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January 1990 in “Clinical Endocrinology” Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.
31 citations
,
February 1997 in “The Journal of Clinical Endocrinology and Metabolism” People who carry the 21-Hydroxylase Deficiency gene are not more likely to have excessive male hormone levels.
29 citations
,
February 2004 in “Experimental and Clinical Endocrinology & Diabetes” Men with early balding often have hormone levels similar to women with polycystic ovary syndrome.
28 citations
,
November 2017 in “Molecular and cellular endocrinology” Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.
28 citations
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July 2017 in “Journal of Endocrinological Investigation” Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.
28 citations
,
February 2011 in “Clinical Endocrinology” Women with PCOS have unhealthy changes in their cholesterol particles that are not related to their body weight.
27 citations
,
February 2020 in “Journal of Cardiovascular Translational Research” Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.
27 citations
,
October 2016 in “The Journal of Clinical Endocrinology and Metabolism” Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.
26 citations
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January 2020 in “Przegląd Menopauzalny” Menopausal women have higher androgen levels, which can cause symptoms like facial hair growth and low sexual desire.
26 citations
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September 2015 in “Journal of The American Academy of Dermatology” Spironolactone may effectively treat female hair loss, especially with hyperandrogenism signs.
26 citations
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April 2003 in “PubMed” Hair loss in two ferrets was caused by ovarian tissue tumors, not adrenal issues.
26 citations
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March 2001 in “PubMed” Men's fertility and sexual health decline with age, with reduced testosterone and virility, and many lose fertility by their eighties.
25 citations
,
September 2006 in “Birth Defects Research” Different processes create patterns in skin and things like hair and feathers.