75 citations
,
September 2017 in “Developmental biology” The circadian clock influences the behavior and regeneration of stem cells in the body.
71 citations
,
January 2014 in “Journal of Proteome Research” Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.
61 citations
,
January 2015 in “Hormones” Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.
53 citations
,
January 2007 in “Dermatology” Chemotherapy often causes patterned hair loss, with some scalp areas more resistant to hair loss than others.
44 citations
,
January 2008 in “Fertility and Sterility” Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.
42 citations
,
January 2011 in “European Journal of Dermatology” Early balding men may have insulin resistance, but lifestyle changes can help.
40 citations
,
January 2013 in “Frontiers in Endocrinology” Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.
38 citations
,
February 2019 in “Clinical Interventions in Aging” Dutasteride more effectively treats hair loss than finasteride, but may increase risk of altered libido.
33 citations
,
July 1992 in “Journal of Investigative Dermatology” Minoxidil doesn't affect perifollicular lymphoid infiltration in alopecia areata patients.
31 citations
,
June 2015 in “British Journal of Dermatology” Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.
31 citations
,
January 2014 in “Clinical Endocrinology” The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.
30 citations
,
July 2022 in “Scientific Reports” Obesity and lifestyle strongly affect heart aging.
30 citations
,
June 2021 in “British Journal of Dermatology” Mutations in the WNT10A gene can cause skin, hair, teeth, and other disorders, and may also affect other areas like kidney and cancer, with potential for targeted treatments.
27 citations
,
January 1984 in “Pharmacology & Therapeutics” Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
25 citations
,
January 2006 in “Pharmacoepidemiology and drug safety” SSRIs can cause hair loss, especially sertraline, with higher risk in women.
24 citations
,
August 2005 in “Health and Quality of Life Outcomes” Women with androgenetic alopecia experience worse physical well-being and quality of life, but similar mental health compared to those without it.
22 citations
,
January 2008 in “Physiological Research” Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.
21 citations
,
May 2016 in “The Cochrane library” Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.
20 citations
,
December 2016 in “American Journal of Clinical Dermatology” Men prefer less invasive cosmetic procedures and need different treatment approaches than women.
20 citations
,
January 2012 in “International Journal of Trichology” Most cases of excessive hair growth in women are caused by polycystic ovarian syndrome and are linked to higher free testosterone levels.
16 citations
,
January 2011 in “Archives of Dermatological Research” The study found that expanded skin regenerates similarly to normal skin, with 77 genes playing a role in the process.
12 citations
,
December 2012 in “Current Drug Targets” The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.
10 citations
,
June 2024 in “American Journal of Clinical Dermatology” Hedgehog pathway inhibitors for advanced basal cell carcinoma can cause side effects, but managing them helps maintain treatment.
10 citations
,
January 2023 in “Acta dermato-venereologica” Baricitinib and deuruxolitinib are effective for treating alopecia areata, but their efficacy depends on the dose.
10 citations
,
November 2015 in “American Journal of Primatology” Monkeys with more anxious or inhibited temperaments tend to have less hair loss.
10 citations
,
January 2015 in “Przeglad Menopauzalny” Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.
10 citations
,
January 2013 in “Faṣlnāmah-i bīmārīhā-yi pūst” Vitamin D levels are not linked to alopecia areata.
9 citations
,
December 2014 in “Neuropsychiatric Disease and Treatment” People with first-time vitiligo have lower levels of a certain brain protein compared to healthy individuals.
8 citations
,
October 2010 in “Scandinavian Journal of Clinical & Laboratory Investigation” Normal-range ALT levels can indicate metabolic and hormonal imbalances in young women.
7 citations
,
January 2013 in “BioMed research international” Hair follicles and deer antlers regenerate similarly through stem cells and are influenced by hormones and growth factors.