130 citations
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September 1990 in “Journal of the American Academy of Dermatology” Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.
23 citations
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March 2010 in “Actas Dermo-Sifiliográficas” Men with early-onset baldness have a higher chance of heart disease and clogged arteries.
20 citations
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December 1994 in “Fertility and sterility” Flutamide combined with a low-dose birth control pill effectively reduces excessive hair growth in women with polycystic ovarian disease.
5 citations
,
December 2021 in “Scientific Reports” Age affects how certain proteins involved in COVID-19 infection are expressed in mice, but sex hormones and heart injury do not.
December 2025 in “International Journal of Infertility & Fetal Medicine” Metformin helps treat PCOS by improving fertility, reducing symptoms, and regulating periods.
228 citations
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January 2021 in “Journal of Neuroimmune Pharmacology” Men have more severe COVID-19 outcomes than women.
120 citations
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June 2008 in “American Journal of Epidemiology” A simple screening method found that 6.3% of women in a semiurban area in Sri Lanka have polycystic ovary syndrome, with most showing menstrual irregularities.
114 citations
,
March 2018 in “PLOS Medicine” Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.
74 citations
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April 2002 in “PubMed” Both oral contraceptives reduced acne effectively and had similar positive effects on skin oiliness and hair growth.
50 citations
,
May 2018 in “International journal of cardiology” Testosterone is linked to cardiovascular risk factors and stroke, but its exact role is unclear.
50 citations
,
March 2001 in “Clinics in Dermatology” Genes and hormones cause hair loss, with four genes contributing equally.
28 citations
,
February 2011 in “Clinical Endocrinology” Women with PCOS have unhealthy changes in their cholesterol particles that are not related to their body weight.
26 citations
,
September 2015 in “Journal of The American Academy of Dermatology” Spironolactone may effectively treat female hair loss, especially with hyperandrogenism signs.
13 citations
,
November 2012 in “PubMed” 5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.
9 citations
,
January 2019 in “Postepy Dermatologii I Alergologii” The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.
3 citations
,
June 2017 in “Reproductive biomedicine online” A certain mutation in the fetal alpha 5-reductase gene is linked to a higher risk of late miscarriage.
November 2025 in “Open Access CRIS of the University of Bern” Androgen levels are more linked to body size in boys than girls.
November 2025 in “European Journal of Endocrinology” Hair steroid profiling is a feasible, non-invasive alternative to serum analysis for assessing hormone levels and metabolism.
May 2025 in “Journal of Investigative Medicine” FAI is a better marker for predicting female hair loss than testosterone or SHBG alone.
October 2023 in “Journal of the Endocrine Society” Losing weight and taking birth control pills can greatly improve severe male hormone excess in women with PCOS.
May 2021 in “Journal of the Endocrine Society” A rare ovarian cancer with a good outlook was found in a woman with unusual hair growth and abdominal symptoms.
Spironolactone with an oral contraceptive improved hair growth in women with hirsutism.
September 2002 in “Fertility and sterility” Metformin can start ovulation and may lower 17P response in PCOS, but six months is too short to improve hair growth or change body fat distribution.
September 2018 in “Fertility and Sterility” The HSD3B1 variant increases hair loss risk in overweight women with PCOS.
May 2017 in “Endocrine Abstracts” Men with early hair loss and certain health factors may have a higher risk of developing reproductive issues, similar to polycystic ovary syndrome in women.
205 citations
,
July 2009 in “Journal of Dermatological Science” Male and female skin differ in many ways, which could lead to gender-specific skin treatments.
January 2018 in “Springer eBooks” Gender affects hair and scalp characteristics, with differences in hormone responses, graying patterns, and trace metals.
41 citations
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April 2006 in “Hormone and metabolic research” Steroid-binding globulins have important roles beyond just transporting steroids.
1 citations
,
September 2017 in “Zhonghua neifenmi daixie zazhi” Routine genetic testing is crucial for early diagnosis and better management of Turner’s syndrome with 21-hydroxylase deficiency.
August 2024 in “Journal of Animal Science and Technology” Angora goat hair growth is influenced by gene expression, sex hormones, and breed differences.