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Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

Sex hormones affect brain injury differently in males and females.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Cyclosporine A therapy changes sex hormone levels differently in pre-menopausal and post-menopausal women with primary biliary cirrhosis.

Low testosterone may increase COVID-19 severity in men.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.

A young woman's rare ovarian tumor was successfully removed, improving her hormonal symptoms.

Some ovarian tumors can cause masculinization, and it's important to check for various causes when this symptom is present.

Depressed teens have different steroid levels in urine, which may help identify and treat them.

Sex hormones do not cause oral lichen planus.

Intralesional steroids improve Alopecia Areata, and trichoscopy effectively tracks this improvement.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

People with hair loss have higher risk of high blood sugar and diabetes, and lower levels of a specific hormone.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Sex-determining genes may affect male baldness.

A young woman had a rare, aggressive ovarian tumor that was hard to diagnose and treat, leading to disease progression despite treatment.

Ovarian steroid cell tumors should be considered in adults with hirsutism and high testosterone, with surgery as the main treatment.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.