Comparison of Trichoscopic Features of Alopecia Areata Before and After Treatment with Intralesional Steroids

March 2025 in “ Pakistan Journal of Health Sciences ”

Shahana Hoor, Zahid Rafiq, Syed Ahmad Ali Gardezi, Humaira Kousar

Alopecia Areata intralesional steroids trichoscopy triamcinolone acetate SALT Score black dots exclamation mark hairs yellow dots short vellus hair circle hair steroid injections trichoscopic examination

TLDR Intralesional steroids improve Alopecia Areata, and trichoscopy effectively tracks this improvement.

This study evaluated the effectiveness of intralesional steroids in treating Alopecia Areata by comparing trichoscopic features before and after treatment in patients aged 18 to 60 with a SALT Score of less than 50. After 12 weeks of treatment with intralesional triamcinolone acetate, there was a significant reduction in the mean SALT Score from 9.91 to 4.94. Trichoscopic features such as black dots, exclamation mark hairs, and yellow dots decreased significantly, while the presence of short vellus hair and circle hair increased. The study concludes that Trichoscopy is a valuable tool for monitoring therapeutic response in Alopecia Areata, as it effectively demonstrates clinical improvement through changes in these features.

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research Alopecia Areata: Understanding the Pathophysiology and Advancements in Treatment Modalities

January 2025 in “Cureus”

Alopecia Areata causes hair loss and needs treatments that address both physical and emotional health.

research The Dermatoscope in the Hair Clinic: Trichoscopy of Scarring and Nonscarring Alopecia

24 citations , August 2023 in “Journal of the American Academy of Dermatology”

Trichoscopy helps diagnose and manage different types of hair loss effectively.

Comparison of Clinical Efficacy and Trichoscopic Changes in Scalp Alopecia Areata Following Treatment with Intralesional Triamcinolone Acetonide and Autologous Platelet-Rich Plasma

research Comparison of Clinical Efficacy and Trichoscopic Changes in Scalp Alopecia Areata Following Treatment with Intralesional Triamcinolone Acetonide and Autologous Platelet-Rich Plasma

July 2023 in “Clinical dermatology review”

Intralesional triamcinolone acetonide is better than PRP for treating scalp alopecia areata, leading to faster and more complete hair regrowth.

research Non-Invasive Techniques for Evaluating Alopecia Areata

June 2023 in “Mædica”

Non-invasive methods can effectively diagnose and manage alopecia areata.

research Utility of Trichoscopy in Comparison to Standard Methods for Assessing Disease Activity, Severity, and Therapeutic Response in Alopecia Areata

1 citations , June 2023 in “Cosmoderma”

Trichoscopy is better than the hair pull test for tracking alopecia areata.

research Trichoscopy Patterns in Alopecia Areata: A Systematic Review and Meta-Analysis

2 citations , June 2023 in “Skin Research and Technology”

Yellow dots and short vellus hairs are the most common signs of Alopecia Areata (AA), and trichoscopy can help diagnose AA and track treatment progress.

research Microneedling With Triamcinolone Acetonide Versus Intralesional Triamcinolone Acetonide in Treatment of Alopecia Areata

February 2023

Microneedling with Triamcinolone acetonide is an effective, less invasive, and safe alternative to direct injections for treating alopecia areata.

research Trichoscopy as an Evaluation Method for Alopecia Areata Treatment: A Comparative Study

12 citations , September 2020 in “Journal of cosmetic dermatology”

Trichoscopy is useful for diagnosing and monitoring alopecia areata treatment.

research Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata

134 citations , July 2020 in “Experimental dermatology”

Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.

research Alopecia Areata: A Multifactorial Autoimmune Condition

148 citations , December 2018 in “Journal of autoimmunity”

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

research Trichoscopy of Alopecia Areata: An Update

89 citations , March 2018 in “The Journal of Dermatology”

Trichoscopy helps diagnose and monitor alopecia areata by looking at a combination of specific hair and scalp features.

research Scalp Dermoscopy or Trichoscopy

69 citations , January 2015 in “Current problems in dermatology”

Trichoscopy is a quick, noninvasive method to diagnose hair and scalp disorders, often reducing the need for biopsies.

research Dermoscopic Evaluation of Therapeutic Response to an Intralesional Corticosteroid in the Treatment of Alopecia Areata

35 citations , January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”

Intralesional triamcinolone acetonide is effective for treating patchy hair loss, and dermoscopy helps detect treatment response and side effects early.