research The Post-finasteride Syndrome: Clinical Manifestation of Drug-Induced Epigenetics Due to Endocrine Disruption
Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.
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research Testosterone Treatment in Women – An Overview
Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.
research The role of androgens in hormone replacement therapy
Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.
research Sexual Dysfunction in Alopecia Areata: A Systematic Review
Hair loss in alopecia areata can negatively affect sexual quality of life.
research Clinical Evaluation of Women Presenting with Low Libido and Determination of Whether Androgen Therapy Might Be Appropriate
Androgen therapy might help some women with low libido, but it has risks and should be used carefully.
research POST-FINASTERIDE SYNDROME AND POST-SSRI SEXUAL DYSFUNCTION: TWO CLINICAL CONDITIONS APPARENTLY DISTANT, BUT VERY CLOSE
Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.
research Finasteride inhibits epinephrine synthesis in humans: implication for sexual dysfunction
Finasteride may cause sexual dysfunction by reducing epinephrine levels.
research Sexual Dysfunction in Polycystic Ovary Syndrome (PCOS): A Biopsychosocial Approach to Assessment and Management
PCOS causes sexual dysfunction, needing comprehensive treatment.
research RETIRED: Managing Menopause Chapter 8 Sexuality and Menopause
Menopause often leads to lower sexual desire and discomfort during sex, but treatment should be personalized and only if it bothers the woman.
research Association of hirsutism and anthropometric profiles with sexual dysfunction and anxiety levels in infertile Indonesian women with polycystic ovarian syndrome
Higher anxiety levels are linked to sexual dysfunction in women with PCOS.
research Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice*
Prolactin affects when mice shed and grow hair.
research Patients treated for male pattern hair with finasteride show, after discontinuation of the drug, altered levels of neuroactive steroids in cerebrospinal fluid and plasma
Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.
research A Review of the FAERS Data on 5-Alpha Reductase Inhibitors: Implications for Postfinasteride Syndrome
The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.
research Maximum Efficacy of Finasteride Is Obtained within 6 Months and Maintained over 6 Years
Finasteride works best in 6 months and lasts 6 years.
research Investigation of the Plausibility of 5-Alpha-Reductase Inhibitor Syndrome
The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.
research Deciphering principles of morphogenesis from temporal and spatial patterns on the integument
The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
research Alterations of gut microbiota composition in post-finasteride patients: a pilot study
Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.
research Post-Finasteride Syndrome: An Induced Delusional Disorder with the Potential of a Mass Psychogenic Illness?
PFS might be a delusional disorder with potential to become mass psychogenic illness.
research New lifestyle drugs and somatoform disorders in dermatology
The article concludes that dermatologists should prescribe lifestyle drugs carefully and consider mental health treatments for patients with disorders like BDD.
research Testosterone in Women: Measurement and Therapeutic Use
Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.
research Nocebo effect in Dermatology
Negative expectations can cause adverse effects in dermatology treatments, like with finasteride for baldness, and careful communication can help reduce these nocebo responses.
research The self in the obsessive–compulsive-related disorders: hoarding disorder, body dysmorphic disorder, and trichotillomania
The conclusion is that self-concept, shame, and emotion regulation are key factors in hoarding disorder, body dysmorphic disorder, and trichotillomania, and should be targeted in treatment and research.
research Safety Profile of Finasteride: Distribution of Adverse Effects According to Structural and Informational Dichotomies of the Mind/Brain
Finasteride can cause sexual dysfunction and depression, which may persist and require hormonal treatment.
research Ongoing Concerns Regarding Finasteride for the Treatment of Male-Pattern Androgenetic Alopecia
Finasteride may cause side effects; more research needed.
research Polycystic ovarian syndrome elevates the distress of sexual pain in Iranian women with infertility
PCOS increases sexual pain and distress in infertile Iranian women.
research Trichotillomania
Trichotillomania is a challenging-to-treat impulse-control disorder where individuals pull out their hair, more common in females, with some treatments showing benefits.
research A Child with Nonscarring Alopecia
A 4-year-old girl was diagnosed with trichotillomania, a condition where she pulls out her hair, which may resolve on its own or require therapy.
research Effects of 5-alpha reductase inhibitors
5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.
research Finasteride withdrawal induces anxiety-like behavior and novelty avoidance in adult male rats.
Finasteride withdrawal causes anxiety-like behavior in male rats.
research Multidimensional assessment of adverse events of finasteride：a real-world pharmacovigilance analysis based on FDA Adverse Event Reporting System (FAERS) from 2004 to April 2024
Finasteride can cause long-term side effects like sexual dysfunction and depression.