February 2023 in “Frontiers in Endocrinology” Too much male hormone in mothers can negatively affect the sexual behavior of both male and female baby mice.
2295 citations
,
August 2012 in “The international journal of transgenderism/International journal of transgenderism” The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.
223 citations
,
December 2010 in “The Journal of Sexual Medicine” Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.
187 citations
,
June 1999 in “Journal of The American Academy of Dermatology” Finasteride effectively treats frontal hair loss with few side effects.
66 citations
,
June 2013 in “Journal of Dermatological Treatment” Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.
58 citations
,
January 2013 in “The Journal of Clinical Endocrinology and Metabolism” Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.
44 citations
,
October 2010 in “BJUI” 5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.
33 citations
,
January 2016 in “Skin appendage disorders” The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.
32 citations
,
March 2019 in “Climacteric” Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.
32 citations
,
February 2016 in “Journal of Dermatology” Dutasteride safely promotes hair growth and reduces hair loss, with mild side effects.
24 citations
,
October 2016 in “Oncotarget” Finasteride has a higher risk of reproductive side effects than minoxidil.
20 citations
,
August 2018 in “The World Journal of Men's Health” Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.
13 citations
,
September 2018 in “Dermatologic Therapy” Finasteride effectively stops hair loss in most patients, but concerns about rare sexual side effects exist.
13 citations
,
June 2018 in “Current Urology Reports” Hair loss drugs may cause sexual issues and infertility in men.
12 citations
,
January 2015 in “Indian Journal of Dermatology, Venereology and Leprology” Negative expectations can cause adverse effects in dermatology treatments, like with finasteride for baldness, and careful communication can help reduce these nocebo responses.
10 citations
,
December 2014 in “PubMed” Finasteride, a hair loss drug, may cause sexual dysfunction and depression, but these effects are usually temporary and the drug is generally safe. More research is needed.
8 citations
,
July 2018 in “Current Sexual Health Reports” Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.
8 citations
,
February 2017 in “Clinical Drug Investigation” Finasteride can cause sexual dysfunction and depression, which may persist and require hormonal treatment.
7 citations
,
June 2020 in “Translational Andrology and Urology” Finasteride for hair loss may cause lasting sexual, genitourinary, mental, and anti-androgenic side effects in young men.
5 citations
,
November 2020 in “JAMA Dermatology” Finasteride may cause side effects; more research needed.
5 citations
,
January 2020 in “Skin appendage disorders” Oral dutasteride works better for hair loss, but has more sexual side effects; intralesional dutasteride is a possible alternative.
4 citations
,
March 2022 in “Journal of The American Academy of Dermatology” Finasteride use in young men with hair loss is linked to sexual dysfunction.
2 citations
,
March 2018 in “Current Opinion in Urology” 5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.
2 citations
,
April 2017 in “European Urology” Using finasteride for hair loss or prostate issues does not significantly raise the risk of erectile dysfunction.
1 citations
,
April 2025 in “Journal of Clinical Medicine” Hair loss in alopecia areata can negatively affect sexual quality of life.
1 citations
,
January 2020 in “Skin appendage disorders” Finasteride is safe for hair loss treatment and doesn't increase high-grade prostate cancer risk.
January 2026 in “Journal of Dermatological Treatment” Oral finasteride may cause more sexual side effects than expected, possibly due to negative publicity and reporting bias.
December 2025 in “Biomedicines” Addressing body image and weight can help improve female sexual dysfunction.
October 2025 in “Open Repository of the University of Porto (University of Porto)” Pharmacists play a crucial role in personalized therapy, health literacy, and patient care across various health conditions.
May 2024 in “Brazilian Journal of Hair Health” Finasteride and dutasteride may help prevent hair loss but could cause side effects like sexual dysfunction and psychological issues.