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research Abstract 1835: Development of mammary hyperplasia, dysplasia, and invasive ductal carcinoma in transgenic mice expressing the 8p11 amplicon oncogene NSD3 (WHSC1L1)

1 citations , July 2017 in “Cancer Research”

Overexpressing NSD3 in mice causes breast cancer-like tumors and gland abnormalities.

research Lnc056 Enhances Hair Follicle Stem Cells Proliferation by Binding Transcription Factor HNRNPUL1 to Up-Regulate TRIP6 Expression.

June 2025 in “PubMed”

Lnc056 helps hair follicle stem cells grow by increasing TRIP6 expression.

research SOX18 Promotes the Proliferation of Dermal Papilla Cells via the Wnt/β-Catenin Signaling Pathway

1 citations , November 2023 in “International Journal of Molecular Sciences”

SOX18 helps sheep hair cells grow by activating a specific cell growth pathway.

research Transcription Regulation and Protein Subcellular Localization of the Truncated Basic Hair Keratin hHb1-ΔN in Human Breast Cancer Cells

8 citations , June 2001 in “Journal of Biological Chemistry”

A truncated protein linked to breast cancer may change cell adhesion.

research Over-, ectopic-expression of FoxN1 at early life adversely influences lymphopoiesis (HEM3P.280)

May 2014 in “The journal of immunology/The Journal of immunology”

Early over-expression of FoxN1 harms immune and skin development.

research Identification and dissection of an enhancer controlling epithelial gene expression in skin

29 citations , February 2001 in “Proceedings of the National Academy of Sciences”

A specific DNA region controls skin cell gene expression by working with certain proteins.

research Analyse de la régulation du gène Hairless et identification des voies de signalisation affectées chez les mutants «bald Mill Hill».

January 2008 in “HAL (Le Centre pour la Communication Scientifique Directe)”

The mutant HR bmh protein affects hair follicle formation by failing to repress vitamin D receptor activity.

research Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis

10 citations , August 2013 in “Experimental Dermatology”

Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.

research miR-133a-3p and miR-145-5p co-promote goat hair follicle stem cell differentiation by regulating NANOG and SOX9 expression

November 2023 in “Animal Bioscience”

miR-133a-3p and miR-145-5p help goat hair follicle stem cells differentiate by controlling NANOG and SOX9.

research Circ 0020938 inhibits hair follicle stem cells proliferation via the miR-142-5p/DSG4 axis in cashmere goats

May 2025 in “BMC Genomics”

Circ 0020938 slows down hair growth in cashmere goats.

research HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression

132 citations , February 2002 in “Journal of Biological Chemistry”

HOXC13 is crucial for regulating hair keratin genes in hair follicles.

research Ornithine Decarboxylase Expression Leads to Translocation and Activation of Protein Kinase CK2 in Vivo

52 citations , May 1997 in “Journal of Biological Chemistry”

High ornithine decarboxylase levels may lead to hair loss and cancer by increasing CK2 activity in the nucleus.

research Identification of androgen-regulated genes in SV40-transformed human hair dermal papilla cells

12 citations , May 2003 in “Journal of dermatological science”

Hsc70 protein may influence hair growth by responding to androgens.

research Hair Cycle-Dependent Expression of Hepatocyte Growth Factor (HGF) Activator, Other Proteinases, and Proteinase Inhibitors Correlates with the Expression of HGF in Rat Hair Follicles

33 citations , December 1999 in “Journal of Investigative Dermatology Symposium Proceedings”

research The Mammalian Hairless Protein as a DNA Binding Phosphoprotein

6 citations , June 2016 in “Journal of cellular biochemistry”

The Hr protein binds to DNA, interacts with p53, and affects cell cycle genes.

research Cyclooxygenase-2 overexpression in the skin of transgenic mice results in suppression of tumor development.

113 citations , May 2002 in “PubMed”

Overexpressing COX-2 in mice skin reduces skin tumor development.

research TSH is a novel neuroendocrine regulator of selected keratins in the human hair follicle

14 citations , June 2011 in “Journal of Dermatological Science”

TSH influences keratin expression in human hair follicles.

research Correction of ornithine transcarbamylase (OTC) deficiency in spf‐ash mice by introduction of rat OTC gene

14 citations , February 1991 in “FEBS Letters”

Introducing the rat OTC gene partially corrected OTC deficiency in mice.

research PSAT1 regulates hair follicle growth and stem cell behavior in cashmere goats

1 citations , April 2025 in “BMC Veterinary Research”

PSAT1 is key for hair growth and stem cell function in cashmere goats.

research CtBP1 Overexpression in Keratinocytes Perturbs Skin Homeostasis

9 citations , November 2013 in “Journal of Investigative Dermatology”

Overexpressing CtBP1 in skin cells causes skin and hair problems.

research Overexpression of human keratin 16 produces a distinct skin phenotype in transgenic mouse skin

25 citations , September 1995 in “Biochemistry and Cell Biology”

High levels of human keratin 16 in mice cause skin lesions and abnormal skin development.

research Sry Transcript Expression in Five Adult Male Rat Tissues and Correlation with Acsl3 Transcript Expression

December 2010 in “OhioLink ETD Center (Ohio Library and Information Network)”

Sry may regulate fatty acid metabolism and shows different expression levels in rat tissues.

research Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours

638 citations , October 1997 in “Nature”

research A 5'-upstream region of a bovine keratin 6 gene confers tissue-specific expression and hyperproliferation-related induction in transgenic mice.

46 citations , May 1995 in “Proceedings of the National Academy of Sciences”

A specific gene region can control targeted and responsive gene expression in mice, useful for skin disorder treatments.

research The hairless (hr) gene is involved in the congential hypotrichosis of Valle del Belice sheep

January 2002 in “Agritrop (Cirad)”

The hr gene is linked to hair loss in Valle del Belice sheep.

research Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin

88 citations , August 1998 in “Carcinogenesis”

High levels of ODC and a mutant Ha-ras gene cause tumors in mice.

research Heterogeneity of ornithine decarboxylase expression in 12-O-tetradecanoylphorbol-13-acetate-treated mouse skin and in epidermal tumors

37 citations , January 1986 in “Carcinogenesis”

ODC expression in mouse skin and tumors is varied and can be inhibited by retinoic acid or cycloheximide.

research Mitogen‐regulated protein/proliferin mRNA induction following single applications of tumor promoters to murine skin

May 2005 in “Molecular Carcinogenesis”

mrp/plf-mRNA can indicate tumor-promoting effects in skin.

research Knockdown of miR-361-5p promotes the induced activation of SHF-stem cells through FOXM1 mediated Wnt/β-catenin pathway in cashmere goats

1 citations , May 2024 in “Animal Biotechnology”

Reducing miR-361-5p boosts hair growth in cashmere goats by activating stem cells.

research Heme Oxygenase and the Skin in Health and Disease

9 citations , July 2018 in “Current Pharmaceutical Design”

HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.

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