54 citations
,
May 2001 in “Journal of Investigative Dermatology” Excessive putrescine causes hair loss in transgenic mice by disrupting hair follicle development.
Hair follicles can be used to quickly assess drug effects in cancer treatment.
2 citations
,
July 2024 in “Indian Journal of Dermatology” Adults with alopecia areata often have empty follicular openings, while children show more honeycomb pigment patterns.
1 citations
,
February 2009 in “Journal of Investigative Dermatology” Lipase H is important for hair follicle function and shaping hair fibers.
January 2014 in “European Journal of Dermatology” A method was found to visualize hair regrowth and avoid unnecessary side effects from treatments.
10 citations
,
April 2013 in “Journal of Investigative Dermatology” Scientists created a model using sheep cells to study hair root formation, which can test how different substances affect hair growth.
1 citations
,
January 1997 in “Skin Pharmacology and Physiology” Premature infants have less elastic hair than full-term infants.
14 citations
,
March 1995 in “Journal of cell science” SV40 T antigen in hair follicles causes abnormal hair and health issues in mice.
June 2026 in “Advanced Science” New cryomicroneedles can improve hair growth and regeneration.
April 2021 in “Journal of Investigative Dermatology” A trial showed that a new treatment is safe and effective for male pattern baldness, with most participants growing new hair.
December 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Hedgehog signaling controls hair follicle development and can affect skin cancer growth.
2 citations
,
March 1989 in “International Journal of Dermatology”
January 2012 in “International Journal of Trichology” Two siblings have a rare genetic condition causing curly, coarse hair.
184 citations
,
November 2014 in “Developmental Cell” Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.
1 citations
,
December 2021 in “Development & Reproduction” Lack of FPR2 slows hair growth by affecting hair cell activity.
May 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Age-related hair loss is linked to the decline and dysfunction of hair follicle stem cells.
25 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Phototrichogram and hair diameter measurements are effective, noninvasive ways to assess hair growth and detect early hair loss, with the most common pattern being reduced hair density.
42 citations
,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
12 citations
,
July 2014 in “Journal of Investigative Dermatology” Chemotherapy causes complex changes in hair follicle cells that can lead to hair loss.
Understanding hair follicle communication can help treat hair loss.
1 citations
,
March 2007 in “Hair transplant forum international” Use hair-styling methods to hide thinning hair after surgery in women.
August 2021 in “Journal of the American Academy of Dermatology” The shampoo's ingredients' effect on a hair growth pathway in cells was tested, but the results are not given.
Dutasteride and finasteride can change hair growth genes, helping treat hair loss.
8 citations
,
March 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” The near-naked hairless mutation causes hair loss but is not due to a mutation in the hairless gene itself.
5 citations
,
May 2015 in “JRSM open” If a child is losing a lot of eyelashes and it keeps happening, doctors should look carefully at their health history because it might be a sign of a different health problem.
Loose anagen syndrome causes easy hair shedding in children, often resolving on its own.
1 citations
,
April 2018 in “Journal of Investigative Dermatology” Lower proximal cup cells, not bulge stem cells, regenerate hair follicles after chemotherapy.
67 citations
,
August 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Androgens promote beard growth but cause hair loss in androgenetic alopecia, with TGF-β1 as a potential treatment target.
24 citations
,
July 1987 in “Dermatologic Clinics” Systemic diseases can cause hair loss, which is often reversible with treatment.
8 citations
,
January 2014 in “BioMed Research International” Eclipta alba extract was found to be effective in promoting hair growth in hairless mice.