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The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Patients with HR+/HER2- advanced breast cancer commonly experience fatigue, hair loss, and pain, which significantly affect daily activities.

Vismodegib is effective for basal cell carcinoma but has severe side effects.

Ultrasound pre-treatment improved the color, taste, and protein quality of fish protein extracts.

Venlafaxine can cause urinary incontinence in rare cases.

Low-dose oral minoxidil for hair loss seems to have rare side effects, but more research is needed to confirm its safety.

Finasteride treats baldness but may cause lasting sexual side effects.

Retinoids might cause temporary hyperthyroidism in some patients.

Serenoa repens may cause long-lasting sexual and psychiatric side effects.

Oral supplements like Vitamin E and Omega-3 can help reduce isotretinoin side effects.

Topical finasteride is well-tolerated and satisfies most users with minimal side effects.

Most patients were satisfied with topical finasteride, and few experienced side effects.

GLP-1 receptor agonists can cause skin and hair issues due to rapid weight loss, but these can be managed with proper care and treatments.

Certain blood markers can help predict and manage chemotherapy side effects in older cancer patients.

Oral minoxidil is easier to use and more satisfying for hair loss treatment but may cause more unwanted hair growth.

Isotretinoin may cause temporary, reversible facial hair growth in some women.

Reviewers criticized the study's methods and suggested focusing on drug mechanisms instead of repositioning due to social media data quality concerns.

Reviewers suggested the study on finding new drug uses through social media side-effects needs better methods and clearer limitations.

The peer review highlighted the need for clearer data handling, questioned the study's validity, and recognized improvements from the original version.

Reviewers criticized the study for its assumptions, social media data collection issues, and lack of comparison to existing methods.

The study improved and was accepted despite initial concerns about data clarity, methodology, and potential overfitting.

Finasteride can rarely cause tinnitus and deafness.

Finasteride, a hair loss drug, has unaddressed sexual side effects due to the manufacturer's inadequate safety measures and lack of additional studies.

FUE and FUT hair transplants have similar success rates, with FUE slightly better.

Tyrosine kinase inhibitors effectively treat cancers but often cause skin and other side effects.

Finasteride use may lead to less alcohol consumption in men with lasting sexual side effects.

Onychomycosis treatment needs personalized, ethical decisions considering patient needs and costs.