research Systemic subchronic toxicity and comparison of four selenium nutritional supplements by 90-day oral exposure in Sprague-Dawley rats
High doses of some selenium supplements caused liver and reproductive harm in rats.
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570-600 / 1000+ results research Selective androgen receptor modulators: a critical appraisal
SARMs show promise but need more evidence to prove they're better than traditional androgens.
research Reproducibility of high-resolution laser speckle contrast imaging to assess cutaneous microcirculation for wound healing monitoring in mice
LSCI-HR is reliable for monitoring blood flow in wound healing in mice.
research Citalopram and finasteride with the lot number FI0510058-A have been voluntarily recalled by Greenstone, after a labelling error
research 471 Senolytic Potential of Fisetin and ABT Compounds in Dermal Fibroblasts
research Enhancing Low-Light Sports Motion Images with Improved Bilateral Filtering and Auto MSRCR
The method greatly improves low-light sports images' quality and reduces artifacts.
research Impurities in Finasteride: Identification, Synthesis, Characterization and Control of Potential Carry-Over Impurities from Reagents Used for the Process
Two impurities in finasteride were identified and characterized as cyclohexyl and phenyl analogs.
research Synthesis and anticancer activity of phenylpropanoid sucrose esters
Phenylpropanoid sucrose esters show potential as anticancer agents.
research Syndromes of Severe Insulin Resistance (SSIRs)
The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.
research Sky Fruit Seed Crush (SFSC): A potential Source of less Salt Curing of Raw Goatskin
Sky Fruit Seed Crush can preserve goatskin with less environmental impact than traditional methods.
research Fabrication and in vitro evaluation of silk fibroin-folic acid decorated paclitaxel and hydroxyurea nanostructured lipid carriers for targeting ovarian cancer cells: A double sword approach
The new drug carriers show promise for better targeting and treating ovarian cancer.
research Bi-allelic Mutations in LSS, Encoding Lanosterol Synthase, Cause Autosomal-Recessive Hypotrichosis Simplex
Mutations in the LSS gene cause a rare type of hereditary hair loss.
![[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs](/images/research/4eb017dc-711d-4926-bcd0-c3b8f48e3a99/small/19974.jpg)
research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs
ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
research FINASTERIDE AND PSA
research 0871 Skin longevity breakthroughs and targets for cellular age reversal: Sirtuins, key epigenetics regulators
research High spatial resolution study of human skin using synchrotron infrared microscopy: application to the penetration of external agents
External agents penetrate skin more easily in areas with fewer lipids, especially through hair follicles.
research Silk Fibroin‐Based Nanoparticles Blended Fluoridated Hydrogel with Photodynamic Antibacterial for Infected Wound Healing
The new hydrogel dressing effectively kills bacteria and helps wounds heal faster with hair regrowth.
research Rapid formation of multicellular spheroids in double-emulsion droplets with controllable microenvironment
A new method quickly creates controllable cell clusters for tissue engineering and drug testing.
research Protocol for Self-Assembled Human Hair Keratins
research In vivo delivery of CRISPR-Cas9 genome editing components for therapeutic applications
research Developmental characteristics of cutaneous telocytes in late embryos of the silky fowl
Telocytes in silky fowl embryos develop distinct features and connections by the 20th day of incubation.
research Lipid Profile and 5α-Reductase Inhibition Activity of Proprietary Ultrahigh-Pressure Supercritical Carbon Dioxide and Hexane Saw Palmetto Extracts
UHP-sCESr is as effective as HESr for treating BPH symptoms.
research Retinoic acid and dimethyl sulfoxide promote efficient delivery of transgenes to mouse skin by topically transdermal penetration
Retinoic acid and DMSO improve gene delivery to mouse skin for potential hair and skin disease treatment.
research Rapid generation of homogenous tumor spheroid microtissues in a scaffold-free platform for high-throughput screening of a novel combination nanomedicine
A new triple drug system using nanoparticles effectively targets breast tumors in 3D models.
research Experience of using of Sonirid Duo in treatment of patients with BPH
Sonirid Duo effectively treats benign prostatic hyperplasia.
research The Localization of Dehydrogenase Activity and Sulphydryl Groups in Wool and Hair Follicles by the use of Tetrazolium Salts
INT effectively shows enzyme activity and protein groups in wool and hair follicles.
research Dissolving microneedle array patches containing mesoporous silica nanoparticles of different pore sizes as a tunable sustained release platform
Microneedle patches with different pore sizes can effectively deliver drugs and trigger strong immune responses.
research Pathogenesis in pili torti: morphological study
Pili torti hair twists due to uneven outer root sheath cell development.
research Functionalization of Alkenes with Difluoromethyl Nitrile Oxide to Access the Difluoromethylated Derivatives
A new method efficiently modifies alkenes to create useful medicinal compounds.
research Potency of a novel saw palmetto ethanol extract, SPET-085, for inhibition of 5α-reductase II
SPET-085 effectively inhibits an enzyme linked to prostate issues, similar to finasteride.