research Strategies for High-Efficiency Mutation Using the CRISPR/Cas System
Improving CRISPR/Cas systems can make gene editing more efficient and precise.
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research Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization
FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.
research Exosomes in Aesthetic Medicine: An Overview
Exosomes are promising tools in aesthetic medicine for skin and hair regeneration.
research Tissue engineering in burn scar reconstruction
Tissue engineering improves burn scar reconstruction by using skin substitutes and replacing damaged tissues.
research Droplet microfluidics: A tool for biology, chemistry and nanotechnology
Droplet microfluidics improves efficiency and control in chemistry, biology, and nanotechnology.
research Human hair regeneration using organoids and hair-on-chip technologies
Organoids and hair-on-chip technologies show promise for hair regeneration but face clinical challenges.
research Bionanomaterials: Advancements in Wound Healing and Tissue Regeneration
Bionanomaterials from natural sources show promise in improving wound healing and tissue regeneration.
research Gelatin-chondroitin-6-sulfate-hyaluronic acid scaffold seeded with vascular endothelial growth factor 165 modified hair follicle stem cells as a three-dimensional skin substitute
Modified rat stem cells on a special scaffold improved blood vessel formation and wound healing in skin substitutes.
research Stem Cell-Based Tissue Engineering for the Treatment of Burn Wounds: A Systematic Review of Preclinical Studies
Stem cell treatments may improve burn wound healing.
research Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development
Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
research Single follicular unit transplantation reconstructs arrector pili muscle and nerve connections and restores functional hair follicle piloerection
Hair transplant surgery can rebuild muscle and nerve connections, allowing transplanted hairs to stand up like normal hairs.
research Modeling cell–cell communication for immune systems across space and time
The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.
research Epigenetic control of adult stem cell function
Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
research Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate
The extracellular matrix is crucial for controlling skin stem cell behavior and health.
research WNT10A promotes an invasive and self-renewing phenotype in esophageal squamous cell carcinoma
WNT10A helps esophageal cancer cells spread and keep renewing themselves.
research 25 Years of Epidermal Stem Cell Research
Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
research Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells
Researchers found a way to create cells from stem cells that act like human cells important for hair growth and could be used for hair regeneration treatments.
research Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation
Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
research Recent advances on skin‐resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti‐aging and cancer therapies
New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
research Inhibition of T-cell activity in alopecia areata: recent developments and new directions
New treatments targeting T-cell pathways are needed for better alopecia areata management.
research Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition
Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.
research Concise Review: Tissue-Engineered Skin and Nerve Regeneration in Burn Treatment
New methods for skin and nerve regeneration can improve healing and feeling after burns.
research Mast cell deficient and neurokinin-1 receptor knockout mice are protected from stress-induced hair growth inhibition
Certain mice without specific receptors or mast cells don't lose hair from stress.
research Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened
The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.
research Stem cell secretome as a new booster for regenerative medicine
Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.
research Regulation of melanocyte stem cell behavior by the niche microenvironment
The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.
research Hair follicular cell/organ culture in tissue engineering and regenerative medicine
Stem cell therapy is a promising approach for hair regrowth despite potential side effects.
research New substrates for stem cell control
New materials help control stem cell growth and specialization for medical applications.
research Skin cell-derived extracellular vesicles: a promising therapeutic strategy for cutaneous injury
Skin cell-derived vesicles can help heal skin injuries effectively.
research Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch+/− Mice
Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.