41 citations
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June 2013 in “PLOS ONE” Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
118 citations
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January 2016 in “Current Topics in Developmental Biology” The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.
84 citations
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January 2018 in “Biomaterials Science” Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.
57 citations
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August 1997 in “Microscopy Research and Technique” New molecules involved in skin and hair growth were identified, improving understanding and future treatments.
41 citations
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September 1991 in “Medical hypotheses” Prolactin may be important for skin growth and immune function.
13 citations
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April 2022 in “Frontiers in oncology” Melanoma development can be linked to the breakdown of skin's melanin-producing units.
8 citations
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January 2017 in “Methods in molecular biology” Stem cells rearrangement regenerates functional hair follicles, potentially treating hair loss.
7 citations
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May 2022 in “Frontiers in Cell and Developmental Biology” Epigenetic and metabolic changes affect stem cell function and aging in skin.
3 citations
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September 2021 in “Journal of Food Science and Nutrition” Red Ginseng Extract helps hair grow and improves skin health by stimulating cell growth and enhancing the body's antioxidant defense system.
Myeloid cells can turn into skin and hair cells to help heal wounds.
5 citations
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April 2021 in “Biomedicines” The engineered skin substitute helped grow skin with hair on mice.
1 citations
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September 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin organoids from stem cells can help study and treat skin issues but face some challenges.
426 citations
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August 2014 in “Nature Medicine” Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
418 citations
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September 2012 in “Nature” African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.
218 citations
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April 2008 in “Genes & Development” Skin stem cells help repair damage and maintain healthy skin.
169 citations
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January 2018 in “Cell Reports” Scientists grew hair follicles from mouse stem cells in a lab setting.
156 citations
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October 2012 in “Seminars in Cell & Developmental Biology” Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
39 citations
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September 2011 in “Tissue Engineering Part B-reviews” Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.
17 citations
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December 2019 in “Stem Cells International” Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.
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July 2024 in “Current Issues in Molecular Biology” Understanding skin stem cells and their regulation is key to improving skin healing and treating disorders.
1 citations
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January 2019 in “The International Journal of Lower Extremity Wounds” Artificial dermal template treatment can stimulate complete skin and hair follicle regrowth.
February 2025 in “Theranostics” 3D bioprinting with special hydrogels can create artificial skin that heals wounds and regrows hair in mice.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
306 citations
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April 2019 in “International Journal of Molecular Sciences” The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
48 citations
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August 2018 in “Nature Communications” JunB is crucial for maintaining healthy skin and hair follicles.
19 citations
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March 2021 in “Applied Materials Today” Silk gel helps skin heal without scars better than other materials.
6 citations
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January 2016 in “Journal of Stem Cell Research & Therapy” Notch1 signaling is crucial for improving wound healing and skin regeneration by affecting stem cell behavior.
5 citations
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January 2019 in “Elsevier eBooks” Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
March 2015 in “Plastic and reconstructive surgery” Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
65 citations
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February 2017 in “Pflügers Archiv - European Journal of Physiology” Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.