research Molecular principles of hair follicle induction and morphogenesis
Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
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90-120 / 1000+ results research Basal cell carcinoma — molecular biology and potential new therapies
Blocking Hedgehog signaling offers new treatment options for advanced basal cell carcinoma.
research Severe skin toxicity during whole-brain radiotherapy, targeted therapy, and additional drug intake including St. John’s wort skin oil
St. John's wort skin oil may increase skin damage risk during radiotherapy.
research Abstract 4385: Live-imaging the interface between homeostasis and cancer initiation
Mutant cells in hair follicles are influenced by their location and interactions with surrounding cells.
research Hidradenitis Suppurativa/Acne Inversa/Dissecting Terminal Hair Folliculitis
Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.
research Faculty Opinions recommendation of Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation.
A balance between BMP and Wnt signals is crucial for hair follicle stem cell function and hair growth.
research Molecular Mechanisms Regulating Hair Follicle Development
Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
research Phenotypic modulation of human hair matrix cells (trichocytes) by environmental influence in vitro and in vivo.
Human hair cells can change based on their environment, especially interactions with certain skin cells.
research Deciphering a Message from the Nucleus: How Transcription Factors and Spatial Chromatin Interactions Orchestrate Epidermal Differentiation
Key skin cell regulators and gene organization changes are crucial for skin cell development and could help treat skin disorders.
research Diverse Role of OX40 on T Cells as a Therapeutic Target for Skin Diseases
OX40-targeted therapies may help treat skin diseases by reducing inflammation and balancing immune responses.
research Neurobiology, Stem Cell Biology, and Immunology: An Emerging Triad for Understanding Tissue Homeostasis and Repair
The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.
research Mechanisms regulating skin immunity and inflammation
The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
research Regulation of VDR by ΔNp63α is associated with inhibition of cell invasion
ΔNp63α helps control a protein that stops cancer cells from spreading.
research The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches
Fat cells are important for tissue repair and stem cell support in various body parts.
research Emerging nonmetabolic functions of skin fat
Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
research The regenerative potential of skin and the immune system
The skin's immune system helps it regenerate and fight infections.
research Fully functional hair follicle organ regeneration using organ-inductive potential stem cells with an accessory mesenchymal cell population in an in vitro culture system
Scientists successfully regenerated functional hair follicles using specific stem cells and mesenchymal cells.
research Epidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures
Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
research LB1774 Establishing competent morphogenetic fields for tissue pattern regeneration in skin organoids
Skin organoids can regenerate hair by forming specific cell units with certain signals.
research Confocal Laser Scanning Microscopy as a Tool for the Investigation of Skin Drug Delivery Systems and Diagnosis of Skin Disorders
Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
research The role of tight junctions in skin barrier function and dermal absorption
Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
research Polyclonal origin and hair induction ability of dermal papillae in neonatal and adult mouse back skin
Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.
research Epidermal stem cell lineages
Epidermal stem cells are crucial for skin health and problems with them can cause issues like poor wound healing, cancer, and aging.
research Decision letter: Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells
IL-1 signaling is crucial for hair follicle stem cell growth and wound healing.
research Hair follicle markers, expression and modulation: Studies on human scalp skin grafts
Activating cAMP and ATP improves hair growth and strength.
research Interaction between dermal papilla cells and follicular epithelial cells in vitro: effect of androgen
Testosterone increases hair follicle cell growth when beard or axillary skin cells are present together.
research Vascular endothelial cells as signaling niches for epithelial stem cells in the skin
Vascular endothelial cells may significantly influence skin stem cells, but more research is needed.
research Recent advances in the role of neuroregulation in skin wound healing
Neuroregulation is crucial for skin wound healing and can be targeted to improve recovery.
research The orchestrated network of skin photoaging: From intercellular crosstalk to molecular signaling
UV radiation causes skin aging by damaging cells and triggering harmful processes.
research 1349 Stimulation of hair follicle stem cell proliferation through an IL-1α dependent activation of γδT-cells
Certain immune cells, when activated by specific signals, can encourage hair growth.