research Research Techniques Made Simple: Zebrafish Models for Human Dermatologic Disease
Zebrafish are useful for studying and developing treatments for human skin diseases.
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research Gene expression profiling of human keratinocytes exposed to the hair-dying agent, m-aminophenol
m-Aminophenol in hair dye can cause skin cell toxicity and stress responses.
research Roles of the Hedgehog Signaling Pathway in Epidermal and Hair Follicle Development, Homeostasis, and Cancer
The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.
research Mice lacking the epidermal retinol dehydrogenases SDR16C5 and SDR16C6 display accelerated hair growth and enlarged meibomian glands
Mice without certain skin enzymes have faster hair growth and bigger eye glands.
research Functional regeneration strategies of hair follicles: advances and challenges
Hair follicle regeneration is advancing but still faces challenges in stability and clinical use.
research Keratinocytes of the Upper Epidermis and Isthmus of Hair Follicles Express Hemoglobin mRNA and Protein
Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.
research 097 LFA-1 blockade prevents the onset of alopecia areata in C3H/HeJ mice
Blocking LFA-1 prevents hair loss in mice.
research The Dermal Papilla and Hair Follicle Regeneration: Engineering Strategies to Improve Dermal Papilla Inductivity
Improving dermal papilla cells can help regenerate hair follicles.
research GLI2 Is Expressed in Normal Human Epidermis and BCC and Induces GLI1 Expression by Binding to its Promoter
GLI2 activates GLI1, promoting skin tumor growth and hair development.
research Actinic keratosis: a clinical and epidemiological revision
Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.
research Type II Keratins Are Phosphorylated on a Unique Motif during Stress and Mitosis in Tissues and Cultured Cells
Type II keratins are uniquely phosphorylated during stress and mitosis, affecting their structure and function.
research Organoid technology for tissue engineering
Organoid technology helps create mini-organs for studying diseases and testing drugs.
research Type XVII collagen coordinates proliferation in the interfollicular epidermis
Type XVII collagen helps control skin cell growth and could be a target for anti-aging treatments.
research Spontaneous tumour regression in keratoacanthomas is driven by Wnt/retinoic acid signalling cross-talk
Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.
research Keratinocyte-Specific Onset of Serine Protease BSSP Expression in Experimental Carcinogenesis
BSSP may help skin tumors grow and could be a marker or target for skin cancer treatment.
research A Systematic Review of Keratinocyte Secretions: A Regenerative Perspective
Skin cells release substances important for healing and fighting infection, and understanding these could improve skin disorder treatments.
research The Transformative Impact of Extracellular Vesicles on the Cosmetics Industry: A Comprehensive Review
Extracellular vesicles could revolutionize skincare by improving skin repair and anti-aging, but face regulatory and cost challenges.
research Obesity and Wound Healing: Focus on Mesenchymal Stem Cells
Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.
research An exclusive review of melatonin effects on mammalian melanocytes and melanoma
Melatonin may inhibit melanoma growth and has potential as a cancer therapy aid, but its effects on human skin pigmentation need more research.
research Folate receptor β performs an immune checkpoint function in activated macrophages
Folate receptor β helps suppress the immune system in macrophages and affects cancer growth and hair health.
research Reawakening GDNF's regenerative past in mice and humans
Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.
research DNA Methylation as an Epigenetic Memory Keeper during Skin Development and Regeneration
DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.
research A Novel Model System to Identify Cellular and Molecular Defects Underlying Rare Genetic Disorders
The new model helps understand and develop treatments for genetic skin disorders like AEC.
research Exosomes serve as a crucial mediator of epithelial–fibroblast communication during hair follicle morphogenesis in cashmere goats
Exosomes help hair follicle development in cashmere goats.
research Peer Review #2 of "Establishment of an immortalized mouse dermal papilla cell strain with optimized culture strategy (v0.2)"
Researchers improved mouse skin cell culture methods and created a similar immortal cell line, but need to clarify their methods and benefits.
research The human keratins: biology and pathology
Keratins are crucial for cell stability, wound healing, and cancer diagnosis.
research Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice
Dermal adipose tissue in mice can change and revert to help with skin health.
research Gene expression profiling gets to the root of human hair follicle stem cells
Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.
research Significance of stress keratin expression in normal and diseased epithelia
Stress keratins are expressed less in diseased skin and are linked to differentiation, inflammation, and immunity.
research The Molecular Revolution in Cutaneous Biology: Noncoding RNAs: New Molecular Players in Dermatology and Cutaneous Biology
Non-coding RNAs are crucial for skin development and health.