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GlossaryDesquamation

process of shedding dead skin cells from the outer layer

Desquamation is the process by which the outermost layer of the skin, known as the stratum corneum, sheds dead cells. This natural exfoliation helps maintain skin health by removing old cells and making way for new ones, and it can be influenced by various factors such as skin conditions, treatments, and overall health.

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research The Fate of Epidermal Tight Junctions in the stratum corneum: Their Involvement in the Regulation of Desquamation and Phenotypic Expression of Certain Skin Conditions

11 citations , July 2022 in “International Journal of Molecular Sciences”

Tight junctions help control skin shedding and may be targets for treating certain skin conditions.

research Human tissue kallikreins as promiscuous modulators of homeostatic skin barrier functions

84 citations , May 2008 in “Biological Chemistry”

Human tissue kallikreins help regulate skin barrier functions and affect skin health.

research Deciphering the functions of the hair follicle infundibulum in skin physiology and disease

38 citations , September 2014 in “Cell and Tissue Research”

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.

research Accelerated senescence in skin in a murine model of radiation-induced multi-organ injury

19 citations , February 2017 in “Journal of radiation research”

High-dose radiation speeds up aging in skin stem cells.

research Scalp-sparing total skin electron therapy in mycosis fungoides: Case report highlighting technique and outcome

3 citations , March 2016 in “Practical radiation oncology”

Total skin electron therapy is an effective treatment for mycosis fungoides, balancing effectiveness and side effects.

research 601 A quantitative study of desquamation in the stratum corneum

April 2023 in “Journal of Investigative Dermatology”

New method measures skin cell turnover quickly and effectively, showing turnover slows with age and responds more to treatments in older skin.

research Nonmelanoma skin cancer treated with electronic brachytherapy: Results at 1 year

78 citations , January 2013 in “Brachytherapy”

HDR electronic brachytherapy effectively treats nonmelanoma skin cancer with good cosmetic results and minimal side effects.

research Hair follicles modulate skin barrier function

9 citations , June 2024 in “Cell Reports”

Hair follicles play a crucial role in regulating skin barrier function.

research Psoriasiform skin reaction due to Brazilian keratin treatment

2 citations , May 2022 in “International Journal of Trichology”

Brazilian Keratin Treatment can cause skin reactions like redness and scaling, possibly due to formaldehyde.

research 371 Hair follicles are critical modulators of skin barrier function

July 2024 in “Journal of Investigative Dermatology”

Hair follicles are crucial for maintaining skin barrier function.

research Skin Toxicity in Palliative Radiation Therapy

January 2017 in “Elsevier eBooks”

Radiation therapy for cancer often causes skin problems like redness, dryness, and pain.

research Effects of high-power millimeter wave on mice skin at different time points of radiation

January 2011 in “Junshi yixue”

Longer exposure to high-power millimeter wave radiation causes more severe skin damage in mice.

research 837 From genotoxic stresses to skin damage: Distinct, novel mechanisms of skin and hair damage in chemo/radiation therapy

April 2017 in “Journal of Investigative Dermatology”

Chemotherapy and radiation therapy cause skin and hair damage by altering gene expression and signaling pathways.

research The dark and the bright sides of the transcription factor Nrf2 in skin protection and disease (Nrf2 and epidermal barrier function)

August 2015 in “Free Radical Biology and Medicine”

Nrf2 helps protect skin from damage but too much can cause skin problems.

research Key Factors in the Complex and Coordinated Network of Skin Keratinization: Their Significance and Involvement in Common Skin Conditions

2 citations , December 2023 in “International journal of molecular sciences”

Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.

research Acute fish liver intoxication: report of three cases.

7 citations , September 1999 in “PubMed”

Eating grouper fish liver can cause vitamin A poisoning with severe symptoms.

research “Case Report : Early Congenital Syphilis”

January 2026 in “Journal of Comprehensive Science (JCS)”

Early diagnosis and treatment are crucial to prevent severe outcomes in congenital syphilis.

research Vulvovaginal involvement in Netherton syndrome: A case report

January 2024 in “JAAD case reports”

Netherton syndrome can cause severe and chronic vulvovaginal symptoms that may improve with continuous oral contraceptives.

research Trichoscopic Findings of Frontal Fibrosing Alopecia

1 citations , July 2020 in “Benha Journal of Applied Sciences”

Trichoscopy is useful for diagnosing Frontal Fibrosing Alopecia.

research Clinical and demographic characteristics of frontal fibrosing alopecia in a dermatology referral center in Bogota, Colombia: a descriptive cross-sectional study

November 2024 in “International Journal of Women’s Dermatology”

Frontal fibrosing alopecia in Bogotá mainly affects postmenopausal women, with possible links to hormonal changes and sunscreen use.

research Daclizumab

August 2019 in “Reactions Weekly”

Daclizumab may cause psoriasis-like skin problems in multiple sclerosis patients.

Man-Made Disease: Clinical Manifestations of Low Phenylalanine Levels in an Inadequately Treated Phenylketonuria Patient and Mouse Study

research Man made disease: Clinical manifestations of low phenylalanine levels in an inadequately treated phenylketonuria patient and mouse study

13 citations , January 2013 in “Molecular genetics and metabolism”

Proper diet management is crucial for phenylketonuria patients to avoid severe health issues.

research Cutaneous manifestations of methylmalonic and propionic acidaemia: a description based on 38 cases

49 citations , July 1994 in “British journal of dermatology/British journal of dermatology, Supplement”

Some children with methylmalonic and propionic acidaemias have skin problems related to their condition and diet.

research Safety of High-Dose Vitamin A

39 citations , January 1991 in “Oncology”

High-dose vitamin A was safe and well-tolerated in a lung cancer treatment study.

The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling

research The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling

146 citations , May 2002 in “The American journal of pathology”

Cathepsin L is essential for normal hair growth and development.

research Cutaneous Side Effects in Non-Small Cell Lung Cancer Patients Treated with Iressa (ZD1839), an Inhibitor of Epidermal Growth Factor

116 citations , December 2003 in “Acta Dermato Venereologica”

Iressa often causes skin issues like acne and dryness in lung cancer patients.

research Adipose-derived stem cells alleviate radiation-induced dermatitis by suppressing apoptosis and downregulating cathepsin F expression

50 citations , August 2021 in “Stem Cell Research & Therapy”

Adipose-derived stem cells help heal radiation skin damage by reducing cell death and inflammation.

research A Case of Cicatricial Alopecia Associated with Erlotinib

25 citations , January 2011 in “Annals of Dermatology”

Erlotinib can cause hair loss as a side effect.

research Oral Lichen Planus

7 citations , July 2013 in “InTech eBooks”

Oral lichen planus is a chronic disease causing mouth discomfort and sometimes needs immunosuppressive treatment.

research Generalized Alopecia with Vasculitis-Like Changes in a Dog with Babesiosis

6 citations , January 2013 in “Journal of Veterinary Medical Science”

The dog's skin and anemia issues returned after stopping treatment for Babesia gibsoni.