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GlossarySkin Firmness

ability of skin to resist deformation and maintain shape

Skin firmness refers to the skin's ability to resist deformation and maintain its shape. It is largely determined by the presence and quality of collagen and elastin fibers in the dermis, which provide structural support and elasticity. As we age, the production of these proteins decreases, leading to sagging and less firm skin.

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research Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence

136 citations , May 2016 in “Phytotherapy Research”

Turmeric may have benefits for skin health, but more research is needed to confirm its effectiveness.

A Review of Aging and an Examination of Clinical Methods in the Assessment of Aging Skin. Part 2: Clinical Perspectives and Methods

research A review of ageing and an examination of clinical methods in the assessment of ageing skin. Part 2: Clinical perspectives and clinical methods in the evaluation of ageing skin

78 citations , September 2008 in “International Journal of Cosmetic Science”

The document concludes that various clinical methods are used to assess ageing skin and the effectiveness of anti-ageing products.

research Follicular Unit Excision in Patients of African Descent: A Skin-Responsive Technique

7 citations , August 2023 in “Dermatologic Surgery”

A new device improves hair transplant success for people of African descent by considering skin thickness and firmness.

research Effect of the Hypoxic Chamber Training Series on Skin Characteristics of Overweight and Obese Women

3 citations , September 2023 in “Cosmetics”

Hypoxic training didn't change skin features, but skin barrier function is linked to blood lipid levels.

research Evaluation of the efficacy and safety of a dietary supplement on hair and skin aging in subjects with androgenic alopecia

August 2025 in “http://isrctn.com/”

The supplement may improve hair growth and skin health with some mild risks.

Skin Manifestations and Biophysical Properties in Patients With Morbid Obesity and Changes After Weight Loss: A Two-Year Prospective Study

research 393 Skin manifestations and biophysical properties in patients with morbid obesity and changes after weight loss: A two-year prospective study

April 2023 in “Journal of Investigative Dermatology”

Weight loss surgery improved several skin conditions in obese patients but often caused hair loss.

research The human tri-peptide GHK and tissue remodeling

165 citations , January 2008 in “Journal of biomaterials science. Polymer ed.”

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

research Treatment of scleromyxoedema with hydroxychloroquine

10 citations , January 2003 in “Journal der Deutschen Dermatologischen Gesellschaft”

Hydroxychloroquine helped improve scleromyxoedema in patients, but caused side effects in some.

research A Novel Follicular Unit Excision Device for All-Purpose Hair Graft Harvesting

7 citations , November 2021 in “Clinical, Cosmetic and Investigational Dermatology”

The new hair graft device is faster, more efficient, and reduces damage to hair follicles.

Potential Lipolytic Effect of Panduratin A Loaded Microspicule Serum as a Transdermal Delivery Approach for Subcutaneous Fat Reduction

research Potential Lipolytic Effect of Panduratin A Loaded Microspicule Serum as a Transdermal Delivery Approach for Subcutaneous Fat Reduction

4 citations , November 2023 in “Biological and Pharmaceutical Bulletin”

The serum reduced thigh fat and improved skin firmness.

Efficacy and Tolerability of a Hyaluronic Acid-Based Extracellular Matrix for Labia Majora Rejuvenation and Augmentation: A Pilot Study

research Efficacy and Tolerability of a Hyaluronic Acid-Based Extracellular Matrix for Labia Majora Rejuvenation and Augmentation: A Pilot Study

April 2024 in “Curēus”

Sunekos® effectively improves labia majora appearance and is well-tolerated.

research A New Universal Follicular Unit Excision Classification System for Hair Transplantation Difficulty and Patient Outcome

4 citations , June 2022 in “Clinical, cosmetic and investigational dermatology”

The new SFS Scale predicts hair transplant difficulty using hair and skin types, with thick skin and coily hair being hardest to work with.

research Polynucleotides HPT for Asian Skin Regeneration and Rejuvenation

13 citations , February 2024 in “Clinical Cosmetic and Investigational Dermatology”

Polynucleotides HPT improves Asian skin tone, firmness, and glow safely.

research The combined use of minimally-cross linked hyaluronic acid skin booster and PDO smooth threads for lip rejuvenation (Lip boosting : A therapeutic approach)

1 citations , January 2024 in “Egyptian Dental Journal /Egyptian Dental Journal”

The combined treatment improves lip texture, elasticity, and firmness for up to nine months.

research UTILIZAÇÃO DOS FIOS ABSORVÍVEIS DE POLIDIOXANONA NO REJUVENESCIMENTO FACIAL

July 2023 in “AESTHETIC OROFACIAL SCIENCE”

PDO threads improve skin firmness and elasticity with minimal recovery time.

Topical Application of Bio-Pulsed Avian MSC-Derived Extracellular Vesicles Enhances Hair Regrowth and Skin Rejuvenation: Evidence from Clinical Evaluation and miRNA Profiling

research Topical Application of Bio-Pulsed Avian MSC-Derived Extracellular Vesicles Enhances Hair Regrowth and Skin Rejuvenation: Evidence from Clinical Evaluation and miRNA Profiling

July 2025 in “Current Issues in Molecular Biology”

Bio-Pulsed sEVs improve hair growth and skin rejuvenation.

research Use of platelet rich plasma for skin rejuvenation

28 citations , April 2024 in “Skin Research and Technology”

Platelet-rich plasma (PRP) is effective and safe for improving skin appearance.

research The Effects of an Oral Supplementation of a Natural Keratin Hydrolysate on Skin Aging: A Randomized, Double‐Blind, Placebo‐Controlled Clinical Study in Healthy Women

4 citations , October 2024 in “Journal of Cosmetic Dermatology”

Taking natural keratin supplements improved skin, hair, and nails in women.

research Effect of estrogens on skin aging and the potential role of selective estrogen receptor modulators

67 citations , January 2007 in “Climacteric”

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

research Effect of Marine-Derived Saccharides on Human Skin Fibroblasts and Dermal Papilla Cells

2 citations , May 2023 in “Marine Drugs”

Marine-derived saccharides may help reduce aging effects on skin and hair by promoting cell growth and collagen production.

research Mesotherapy Applications in Dermatology

January 2025 in “Acta Scientific Women s Health”

Mesotherapy can improve skin and hair health by using targeted injections.

Dermatology and Aesthetic Procedures Edition XVIII

research Dermatologia e Procedimentos Estéticos Ed. XVIII

October 2025 in “Editora Pasteur eBooks”

Peptides improve skin health and treatments for hair loss and pregnancy-related skin issues are evolving.