research Beyond acne: Current aspects of sebaceous gland biology and function
The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
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research 1434 Epithelially derived MPZL3 negatively regulates murine and human sebaceous gland size and sebocyte proliferation
MPZL3 protein helps control the size of oil glands and the growth of oil-producing cells in both mice and humans.
research TGFβ signaling regulates lipogenesis in human sebaceous glands cells
TGFβ signaling prevents sebaceous gland cells from producing fats.
research Sdr16c5 and Sdr16c6 control a dormant pathway at a bifurcation point between meibogenesis and sebogenesis
Sdr16c5 and Sdr16c6 genes regulate a key point in lipid production that affects eye and skin gland function.
research Molecular interactions of natural and synthetic steroids in female hamsters’ flank organs
Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.
research Anti-oxidant and Anti-inflammatory Effects of Sinapic Acid in UVB Irradiation-Damaged HaCaT Keratinocytes
Sinapic acid may protect skin cells from UV damage and reduce inflammation, making it a promising anti-aging cosmetic ingredient.
research Functions of peroxisome proliferator‐activated receptors (PPAR) in skin homeostasis
PPARs help regulate skin health and could be used to treat skin disorders.
research The Important Role of Leptin in Modulating the Risk of Dermatological Diseases
Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.
research Reproductive and Nonreproductive Actions of Testosterone
Testosterone is important for male sexual traits, reproduction, muscle and bone health, blood production, and metabolism, and works both directly and after being changed into other hormones.
research Liposomes and Ethosomes: Comparative Potential in Enhancing Skin Permeability for Therapeutic and Cosmetic Applications
Ethosomes enhance skin penetration better than liposomes, benefiting therapeutic and cosmetic applications.
research 896 Androgens activate lipogenesis through an AKT-independent mTOR pathway stimulation and a limitation of autophagy in an androgen-sensitive sebocyte cell line
Dihydrotestosterone (DHT) increases oil production in skin cells by activating mTOR, and mTOR inhibitors can reduce this effect.
research The TRPM5 Antagonist Triphenylphosphine Oxide Increases Sebaceous Lipogenesis and Modulates Immune Phenotype of Human Sebocytes in a TRPM5‐Independent Manner
Triphenylphosphine oxide can increase oil production and reduce inflammation in skin cells without affecting TRPM5.
research Mechanistic insights into 5-aminolevulinic acid photodynamic therapy for acne vulgaris: targeting lipogenesis via the OLR1-Wnt/β-catenin pathway
5-aminolevulinic acid therapy reduces acne by decreasing fat production in skin cells.
research Exosomes in Dermatological Research: Unveiling Their Multifaceted Role in Cellular Communication, Healing, and Disease Modulation
Exosomes could help treat skin and hair issues by improving healing and reducing stress.
research Targeting Cutaneous Cannabinoid Signaling in Inflammation - A “High”-way to Heal?
Enhancing cannabinoid signaling may help treat skin inflammation.
research Ultraviolet B irradiation increases the expression of inflammatory cytokines in cultured sebocytes
UV-B light increases inflammation-related substances in acne-related skin cells.
research The impact of oxidative stress on hair
Oxidative stress damages hair and contributes to aging, and managing it can help maintain hair health.
research Embryonic keratinization in vertebrates in relation to land colonization
Keratinization in embryos helped vertebrates adapt to land by forming a protective skin barrier.
research Current Perspectives on the Physiological Activities of Fermented Soybean-Derived Cheonggukjang
Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.
research TREATMENT OF ACNE VULGARIS, OR EVERYTHING WE SHOULD KNOW ABOUT ISOTRETINOIN
Isotretinoin effectively treats severe acne but has significant side effects requiring careful monitoring.
research 694 Retinoid induced changes in the fatty acid profile of sebum and its effect on bacterial growth
Retinoids change the fat content in skin oil and reduce bacteria growth, helping to treat acne.
research 265 Loss of Langerhans cells in scar lesion of lichen planopilaris is caused by downregulation of integrin αvβ6 in the epidermal keratinocytes
Scarred skin in lichen planopilaris loses immune cells due to a decrease in a specific protein in skin cells.
research Prolactin as a candidate sebotrop(h)ic hormone?
Prolactin may influence skin glands and could be a target for treating acne and skin aging.
research Effect of Hataedock Treatment on Epidermal Structure Maintenance through Intervention in the Endocannabinoid System
Hataedock treatment improved skin health and reduced atopic dermatitis symptoms by enhancing the skin barrier and reducing inflammation.
research Preliminary comparison of skin transcriptome from sheep with different wool fibre diameters
Lipid metabolism affects wool fiber diameter in sheep.
research Surface Lipids as Multifunctional Mediators of Skin Responses to Environmental Stimuli
Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.
research Non-invasive human skin transcriptome analysis using mRNA in skin surface lipids
The conclusion is that analyzing RNA from skin oils is a promising way to understand skin diseases.
research Effects of Sex Steroid Deprivation/Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females
Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.
research The Effect of Particle Size on the Deposition of Solid Lipid Nanoparticles in Different Skin Layers: A Histological Study
Smaller nanoparticles penetrate skin better, especially through hair follicles.
research Regional difference in sebum production by androgen susceptibility in human facial skin
The T-zone on the face has more androgen receptors and produces more oil than the U-zone.