TLDR Ethosomes enhance skin penetration better than liposomes, benefiting therapeutic and cosmetic applications.
This review examines the potential of liposomes and ethosomes in enhancing skin permeability for therapeutic and cosmetic applications. Ethosomes, which contain high ethanol content, outperform liposomes in skin penetration due to their flexibility and ability to disrupt the skin's lipid structure. They are particularly effective for delivering drugs like minoxidil and finasteride directly to hair follicles, aiding in treating conditions such as hair loss. Despite their advantages, ethosomes face challenges like oxidative degradation and high production costs. The review underscores the need for further research to optimize these nanocarriers for transdermal drug delivery systems.
2 citations
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June 2024 in “International Journal of Drug Delivery Technology” Advanced delivery systems can make dithranol more effective and less irritating for treating psoriasis.
July 2023 in “Journal of Cosmetic Dermatology” Ethosomes could improve how well skin treatments work, but more research is needed on their safety and stability.
Optimized carriers effectively deliver Finasteride for hair loss treatment.
67 citations
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January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
2 citations
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January 2022 in “Springer eBooks” 
4 citations
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July 2021 in “Journal of Dermatological Treatment” Finasteride helps hair growth but may cause sexual side effects and depression.
365 citations
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March 2021 in “Frontiers in Bioengineering and Biotechnology” Nanocarriers can improve drug delivery through the skin by overcoming barriers.
151 citations
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November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
