114 citations
,
February 2012 in “International Journal of Dermatology” Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
86 citations
,
April 2016 in “Nature Communications” Notch1 helps skin heal by attracting specific immune cells.
84 citations
,
January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” Skin stem cells help maintain skin health, grow hair, and heal wounds.
74 citations
,
June 2018 in “Cell death and disease” Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.
41 citations
,
September 2012 in “Cellular and Molecular Life Sciences” MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.
40 citations
,
January 2016 in “Elsevier eBooks” The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
35 citations
,
January 2013 in “The Journal of experimental medicine/The journal of experimental medicine” CD98hc's role in skin health decreases with age.
24 citations
,
March 2018 in “Experimental Dermatology” Treg dysfunction is linked to various autoimmune skin diseases, and understanding Treg properties is key for new treatments.
20 citations
,
August 2016 in “International Journal of Cancer” Men with male pattern baldness have a higher risk of certain skin cancers, especially on the scalp.
17 citations
,
December 2015 in “International Journal of Cosmetic Science” Visible light can improve skin disorders and hair loss, but more research is needed to understand long-term effects.
9 citations
,
July 2018 in “Current Pharmaceutical Design” HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.
9 citations
,
January 2017 in “Elsevier eBooks” Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
3 citations
,
August 2021 in “Cutis” Some alternative medicine treatments might work for skin conditions, but their effectiveness and safety differ a lot.
1 citations
,
July 2022 in “Functional foods in health and disease/Journal of functional foods in health & disease” Taking a probiotic supplement twice a day improved hair growth, skin hydration, and metabolic health in adults at risk of metabolic syndrome.
1 citations
,
January 2019 in “Journal of Embryology & Stem Cell Research” MSCs help rejuvenate skin by promoting cell growth and reducing inflammation.
1 citations
,
January 2012 in “Elsevier eBooks” The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.
May 2026 in “The EMBO Journal” Skin aging can be slowed by targeting cells, hormones, and the microbiome.
December 2025 in “Clinical Cosmetic and Investigational Dermatology” ZDHHC17 methylation may help treat or identify facial skin aging.
Menopause-related skin changes may increase fungal infections and inflammation.
Elastin-like recombinamers show promise for better wound healing and skin regeneration.
January 2018 in “Stem cell biology and regenerative medicine” The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
April 2016 in “Journal of Investigative Dermatology” Male pattern baldness is linked to a higher risk of certain skin cancers, especially on the scalp.
January 2015 in “Dermatology Review” LED therapy may improve skin health and stimulate hair growth.
November 2004 in “Medical Journal of Indonesia” Hormonal imbalances can cause skin and hair problems in women, and treatments that block male hormones can help.
110 citations
,
July 2017 in “Immunology” Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.
43 citations
,
February 2019 in “International immunology” Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.
February 2018 in “Trends in Immunology” Skin bacteria can help wound healing by activating certain immune cells.
134 citations
,
January 2019 in “American journal of clinical dermatology” Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.
788 citations
,
February 2007 in “Nature” The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
202 citations
,
August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.