research Regulation of VDR by ΔNp63α is associated with inhibition of cell invasion
ΔNp63α helps control a protein that stops cancer cells from spreading.
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330-360 / 1000+ results research Adipokines in the Skin and in Dermatological Diseases
Adipokines affect skin health and could be targeted for treating skin diseases.
research Dormancy in the stem cell niche
Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.
research Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation
Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.
research Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity
Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
research Carthami flos: a review of its ethnopharmacology, pharmacology and clinical applications
Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.
![[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs](/images/research/4eb017dc-711d-4926-bcd0-c3b8f48e3a99/small/19974.jpg)
research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs
ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
research Hair follicle stem cells as a skin‐organizing signaling center during adult homeostasis
Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
research Cholesterol homeostasis: Links to hair follicle biology and hair disorders
Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
research Cutaneous toxicities of new treatments for melanoma
New melanoma treatments can cause skin side effects, including skin cancer and rashes, but combining treatments may reduce these risks.
research THY1-mediated mechanisms converge to drive YAP activation in skin homeostasis and repair
Targeting THY1 can improve skin repair and healing.
research Group IID, IIE, IIF and III secreted phospholipase A2s
Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
research Expression of Kruppel-Like Factor KLF4 in Mouse Hair Follicle Stem Cells Contributes to Cutaneous Wound Healing
KLF4 is important for maintaining skin stem cells and helps heal wounds.
research Spironolactone and XPB: An Old Drug with a New Molecular Target
Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
research Osteopontin Gene is Expressed in the Dermal Papilla of Pelage Follicles in a Hair-Cycle-Dependent Manner
The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.
research Skin Development and Disease: A Molecular Perspective
Understanding molecular processes in skin development is key to creating targeted treatments for skin disorders.
research Murine Epidermal Ceramide Synthase 4 Is a Key Regulator of Skin Barrier Homeostasis
Ceramide Synthase 4 is crucial for healthy skin barrier function.
research Platelet-Therapeutics to Improve Tissue Regeneration and Wound Healing—Physiological Background and Methods of Preparation
Platelet-rich treatments can help improve wound healing and tissue repair.
research Optical Studies of Nanodiamond-Tissue Interaction: Skin Penetration and Localization
Diamond nanoparticles can penetrate skin and reach hair follicles, useful for imaging applications.
research Prevalence and associated factors of skin cancer in aged nursing home residents: A multicenter prevalence study
Skin cancer is common in elderly nursing home residents, with risk factors including being male, having light skin, outdoor work history, and smoking. Regular skin checks are recommended.
research Cutaneous Toxicities From Transplantation-Related Medications
Skin problems from transplant drugs are common and need careful management in organ transplant patients.
research A review of the sources and pharmacological research of morroniside
Morroniside has many health benefits, including protection against diabetes complications, bone and brain diseases, heart and skin issues, and it supports hair growth and reduces inflammation.
research Vitamin D and the Skin: A Review for Dermatologists
Vitamin D is important for skin health, but more research is needed to understand its full effects and treatment potential.
research Advances in Microengineered Platforms for Skin Research
Skin-on-a-chip devices better mimic human skin for research.
research Contributions of peroxisome proliferator-activated receptor β/δ to skin health and disease
PPAR β/δ is important for skin health and disease treatment, but more research is needed.
research Cell Density-Dependent Upregulation of PDCD4 in Keratinocytes and Its Implications for Epidermal Homeostasis and Repair
PDCD4 is important for controlling skin cell growth and healing.
research The therapeutic promise of apoptosis
Blocking cell death in certain stem cells can improve wound healing and tissue regeneration.
research Montagna Symposium 2014—Skin Aging: Molecular Mechanisms and Tissue Consequences
The symposium concluded that understanding the molecular mechanisms of skin aging could lead to better clinical practices and treatments.
research Initial damage produced by a single 15-Gy x-ray irradiation to the rat calvaria skin
15-Gy x-ray irradiation temporarily alters rat calvaria skin without causing significant inflammation or fibrosis.
research Ontogeny of Skin Stem Cells and Molecular Underpinnings
Understanding skin stem cells and their regulation is key to improving skin healing and treating disorders.