research Dermatological diseases from a genetic perspective
New gene discoveries have improved diagnosis and treatment for skin and hair disorders, but more research is needed to fully understand them.
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research Contact cooling of the skin
Skin can be cooled quickly and safely during laser treatments to protect it without affecting deeper layers.
research The influence of CD26+ and CD26− fibroblasts on the regeneration of human dermo-epidermal skin substitutes
CD26+ fibroblasts improve skin healing and integration better than CD26− fibroblasts.
research Mimicking fat grafting of fibrotic scars using 3D‐organotypic skin cultures
Fat grafting reduces scar fibrosis but may slow skin healing.
research 918 Tissue engineered human hair follicles from genetically, environmentally and extrinsically reprogrammed dermal papilla cells
Researchers developed a method to grow human hair follicles using 3D-printed skin models and modified cells.
research Measurement of Skin Permeation/Penetration of Nanoparticles for Their Safety Evaluation
Nanoparticles don't penetrate intact skin but can enter through pores or damaged skin.
research Understanding Cancer Cells of Origin in Cutaneous Tumors
The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.
research 137 Loss of myeloid Mcpip1 suppresses hair growth and development of epidermal papilloma of the skin
Removing MCPIP1 from myeloid cells in mice leads to hair loss and prevents skin tumors but causes pigmented spots.
research Abstract 5202: Bone marrow-derived epithelial cells contribute to chronic skin inflammation and skin tumor formation in the mouse
Bone marrow-derived cells can lead to skin inflammation and tumors in mice.
research The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development
Fgfr2b helps maintain healthy skin and prevent cancer.
research MSF-VMDNet for multi class segmentation of skin cancer whole slide images using a multi frequency dual encoder network
MSF-VMDNet accurately segments skin cancer images better than existing methods.
research 1439 Development of a complex skin organ in human induced pluripotent stem cell-derived organoids
Scientists created skin-like structures from stem cells that include features like hair and sweat glands.
research Keratin 19 as a biochemical marker of skin stem cells in vivo and in vitro: keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age and culture stage
Keratin 19 helps identify skin stem cells, with its presence varying by body location, age, and culture stage.
research The cell biology of human hair follicle pigmentation
We need more research on human hair follicle pigmentation, not just mouse models.
research Forkhead/winged-helix transcription factor whn regulates hair keratin gene expression: Molecular analysis of theNude skin phenotype
Whn is essential for hair growth, and its malfunction causes hair loss.
research Role of Stearoyl-CoA Desaturase-1 in Skin Integrity and Whole Body Energy Balance
SCD1 is crucial for skin health and overall energy balance.
research Secreted subtilisin Sub3 from Microsporum canis is required for adherence to but not for invasion of the epidermis
Sub3 is essential for fungus adherence but not for skin invasion.
research Meibomian gland changes in the rhino (hrrhhrrh) mouse.
Rhino mice show significant meibomian gland changes, making them a potential model for studying gland disorders.
research Significance of the S100A4 Protein in Psoriasis
The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.
research The use of liposomes in the topical application of steroids
Liposomes are not better than acetone for applying DHT on skin.
research Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation
N-WASP is essential for healthy skin and preventing inflammation.
research Isolation of Stem Cells and Progenitors from Mouse Epidermis
A method was developed to isolate and study hair follicle stem cells from mouse skin.
research Inducible expression of gasdermin A3 in the epidermis causes epidermal hyperplasia and skin inflammation
Gasdermin A3 overexpression in skin causes inflammation and hair loss.
research The mechanotransducer Piezo1 coordinates metabolism and inflammation to promote skin growth
Piezo1 helps skin grow by managing metabolism and inflammation.
research Normalization of hair growth in sparse fur-abnormal skin and hair (SPF-ASH) mice by introduction of the rat ornithine transcarbamylase (OTC) gene
Introducing the rat OTC gene normalized hair growth in SPF-ASH mice.
research Targeted skin delivery of topically applied drugs by optimised formulation design
Optimized formulations with specific ingredients can significantly improve skin delivery of topical drugs.
research Metformin Promotes Mechanical Stretch-Induced Skin Regeneration by Improving the Proliferative Activity of Skin-Derived Stem Cells
Metformin helps improve skin regeneration by increasing the growth of skin stem cells.
research Trends in the global organoid technology and industry: from organogenesis in a dish to the commercialization of organoids
Organoid technology is advancing and entering commercial use, with applications in disease modeling, drug development, and personalized medicine.
research 10×Genomics Single-cell Sequencing Reveals Differential Cell Types in Skin Tissues of Liaoning Cashmere Goats and Key Genes Related Potentially to the Fineness of Cashmere Fiber
The study found specific skin cells and genes that may affect the quality of cashmere in Liaoning Cashmere Goats.
research Skin bacteriota ameliorates androgenetic alopecia via harmonizing skin immuno inflammatory balance
Restoring skin bacteria may help reduce hair loss.