research Exploring the efficacy evaluation model for androgenic alopecia using hair organoids: Transcending conventional hair research
Hair organoids are effective for testing hair loss treatments.
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research Mechanical force drives the initial mesenchymal-epithelial interaction during skin organoid development
Mechanical force is important for the first contact between skin cells and hair growth in mini-organs.
research Microscopy‐guided laser ablation for the creation of complex skin models with folliculoid appendages
Researchers used a laser to create advanced skin models with hair-like structures.
research Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening
The Spherical Skin Model improves drug and cosmetic testing by accurately mimicking human skin for efficient compound screening.
research Hair follicle organoids: advances in construction, applications, and translational challenges
Hair follicle organoids can help study hair biology and disorders but need improvements for wider use.
research Skin Cyst: A Pathological Dead-End With a New Twist of Morphogenetic Potentials in Organoid Cultures
Skin cysts might help advance stem cell treatments to repair skin.
research Understanding skin morphogenesis across developmental, regenerative and evolutionary levels
The article concludes that studying how skin forms is key to understanding skin diseases and improving regenerative medicine.
research Reconstructed human skin shows epidermal invagination towards integrated neopapillae indicating early hair follicle formation in vitro
The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
research Targeting the Complexity of In Vitro Skin Models: A Review of Cutting-Edge Developments
In vitro skin models are improving but still need more innovation to fully replicate human skin.
research Cultured Human Foreskin as a Model System for Evaluating Ionizing Radiation-Induced Skin Injury
Human foreskin does not show aging or reduced cell growth after radiation, and H2A.J is not a good marker for radiation-induced aging.
research A volar skin excisional wound model for in situ evaluation of multiple-appendage regeneration and innervation
The study concluded that the new wound model can be used to evaluate skin regeneration and nerve growth.
research Efficient Generation of Skin Organoids from Pluripotent Cells via Defined Extracellular Matrix Cues and Morphogen Gradients in a Spindle‐Shaped Microfluidic Device
Scientists developed a new way to create skin-like structures from stem cells using a special 3D gel and a device that improves cell organization and increases hair growth.
research Histological characteristics of hair follicles at different hair cycle and in vitro modeling of hair follicle-associated cells of yak (Bos grunniens)
The study provides insights into hair growth mechanisms in yaks.
research Disease-related biomarkers as experimental endpoints in 3D skin culture models
research Cinnamic acid promotes elongation of hair peg-like sprouting in hair follicle organoids via oxytocin receptor activation
Cinnamic acid may help hair grow by activating oxytocin receptors.
research Enhanced Differentiation Potential of Pigmented Human Epidermal Equivalents
PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.
research Mechanical and Immunological Regulation in Wound Healing and Skin Reconstruction
Advances in mechanobiology and immunology could lead to scarless wound healing.
research Modelling Human Hair Follicles—Lessons from Animal Models and Beyond
Improving human hair follicle models is crucial for better hair loss treatments.
research Beyond acne: Current aspects of sebaceous gland biology and function
The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
research Hair follicle stem cells as a skin‐organizing signaling center during adult homeostasis
Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
research Diverse cellular players orchestrate regeneration after wounding
Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
research The role of 3Rs in the age of One Health: where we are and where we’re going
Innovative methods are reducing animal testing and improving biomedical research.
research Biofabrication of Human Skin with Its Appendages
Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
research Synergizing biomaterials and cellular molecular pathways: a new frontier in hair follicle generation
Combining biomaterials and cell pathways can improve hair follicle regeneration.
research The microfollicle: a model of the human hair follicle for in vitro studies
Microfollicles can effectively model human hair follicles for research and testing.
research Skin equivalent assay: An optimized method for testing for hair growth reconstitution capacity of epidermal and dermal cells
The 3D skin model is better for hair growth research and testing treatments.
research Recent advances in understanding the role of the skin microbiome in the treatment of atopic dermatitis
The skin microbiome plays a key role in treating atopic dermatitis.
research Functional ectodermal organ regeneration as the next generation of organ replacement therapy
The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.
research 773 Generation of human hair follicle organoids in vitro and ex vivo by co-culture of primary human hair matrix keratinocytes and dermal papilla fibroblasts
Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.
research Correlation of proteolytic activities of organ cultured intact mouse skin with defined hair cycle stages
Proteolytic activity in mouse skin changes with hair cycle stages, peaking in early anagen.