January 2024 in “RSC pharmaceutics” Removing the outer skin layer increases drug absorption and offers non-invasive treatment options, with some methods allowing for quick skin recovery.
9 citations
,
October 2013 in “Drug Delivery” Ethosomal carriers effectively deliver hair loss drug into skin.
130 citations
,
August 2020 in “Drug Design Development and Therapy” Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
39 citations
,
November 2013 in “European journal of pharmaceutics and biopharmaceutics” Massage increases how deep both rigid and flexible liposomes can go into skin, with flexible ones going deeper, and covering the skin (occlusion) helps rigid ones more.
December 2025 in “Aesthetic Plastic Surgery” The new near-infrared LED device improves skin and hair with no side effects.
21 citations
,
July 2017 in “Journal of Cosmetic and Laser Therapy” Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.
2 citations
,
November 2025 in “Pharmaceutics” Moderately lipophilic dyes penetrate skin deeply, while highly hydrophobic or lipophilic dyes stay on the surface.
June 2024 in “Majallah-i dānishgāh-i ̒ulum-i pizishkī-i Kirmān.” Eucalyptus and Tween 80 most effectively increase cetirizine skin absorption.
25 citations
,
July 2019 in “Journal of drug delivery science and technology” Researchers created better skin-application menthol capsules that are stable, safe, and penetrate the skin quickly.
1 citations
,
November 2004 in “International Journal of Cosmetic Science” External agents penetrate skin more easily in areas with fewer lipids, especially through hair follicles.
55 citations
,
June 2009 in “Journal of Pharmaceutical Sciences” Minoxidil promotes hair growth by penetrating skin, with ethanol-containing formulas working best.
16 citations
,
August 2014 in “Colloids and surfaces. B, Biointerfaces” Lipid-coated silica nanoparticles penetrate human skin more deeply than bare silica nanoparticles.
March 2025 in “Asian Journal of Beauty and Cosmetology” Microspicule cosmetics improve skin whitening, pores, and barrier strength.
48 citations
,
July 2019 in “International Journal of Biological Macromolecules” A new hydrogel with stem cells from human umbilical cords improves skin wound healing and reduces inflammation.
82 citations
,
May 2009 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.
May 2023 in “Current Medicinal Chemistry” Microneedle patches improve drug delivery for skin treatments and cosmetic enhancements.
7 citations
,
October 2024 in “AAPS PharmSciTech” CA-SLN-Ngel significantly reduces cellulite more effectively than regular caffeine gel.
1 citations
,
February 2023 in “Applied sciences” The new topical growth hormone formula has high skin penetration and bioavailability.
527 citations
,
December 2011 in “Proceedings of the National Academy of Sciences” Dextran hydrogels improve burn wound healing and skin regeneration.
47 citations
,
September 2013 in “Aaps Pharmscitech” Improved hair loss treatment using special particles and surfactants.
27 citations
,
September 2018 in “Medicines” Oleic acid nanovesicles improve minoxidil absorption in hair follicles for alopecia treatment.
2 citations
,
August 2023 in “Molecules” SH-340 may improve skin barrier and help treat atopic dermatitis.
148 citations
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May 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice without the vitamin D receptor are more prone to UV-induced skin tumors.
140 citations
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December 2017 in “Journal of Controlled Release” Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.
28 citations
,
March 2014 in “International Journal of Nanomedicine” New lipid nanoparticles show promise for delivering hair loss treatments but need improvement for better skin penetration.
14 citations
,
November 2019 in “Materials” Diamond nanoparticles can penetrate skin and reach hair follicles, useful for imaging applications.
1 citations
,
September 2025 in “Scientific Reports” The new gel improves treatment of tough skin infections.
January 2012 in “Journal of Cosmetics Dermatological Sciences and Applications” Iontophoresis greatly improves skin absorption of certain substances, especially in hairy mice.
49 citations
,
August 2016 in “Aesthetic Surgery Journal” Micro-needling effectively improves wrinkles, scars, and hair growth, but proper technique and safety are important.
May 2024 in “The journal of investigative dermatology/Journal of investigative dermatology” Applying DMG-Na to the skin increases blood flow and may help with skin conditions.