18 citations
,
June 2017 in “Proceedings of the National Academy of Sciences of the United States of America” A gene called Gk5 controls lipid production in the skin and affects hair growth.
2 citations
,
January 2012 in “Hair therapy & transplantation” DDAIP-HCl significantly increases minoxidil absorption into the skin.
268 citations
,
April 2009 in “International Journal of Pharmaceutics” Niosomes improve minoxidil skin delivery for hair loss treatment.
156 citations
,
August 2016 in “Journal of controlled release” Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
151 citations
,
November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
75 citations
,
August 2018 in “Biochemical pharmacology” Targeting the skin's endocannabinoid system could help treat skin disorders.
67 citations
,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
67 citations
,
January 2012 in “Biological and Pharmaceutical Bulletin” Nanoparticles don't penetrate intact skin but can enter through pores or damaged skin.
67 citations
,
August 2007 in “American Journal of Pathology” Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
62 citations
,
October 2010 in “Journal of biomedical nanotechnology” Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.
35 citations
,
January 2018 in “Skin pharmacology and physiology” Nanoemulsion creams with certain enhancers can greatly increase caffeine delivery through skin.
34 citations
,
July 2011 in “International journal of pharmaceutics” Ion-paired risedronate significantly increases skin penetration without irritation compared to risedronate alone.
31 citations
,
September 2014 in “Journal of Pharmaceutical Sciences” Using a special laser can improve how well hair loss treatments get into the skin and hair follicles.
29 citations
,
September 2024 in “AAPS PharmSciTech” Transcutol® helps drugs penetrate the skin more effectively in various formulations.
29 citations
,
June 2018 in “Scientific Reports” 15-lipoxygenase helps keep skin healthy by reducing inflammation.
27 citations
,
July 2015 in “International Journal of Dermatology” Every elderly patient had at least one skin condition, often linked to other diseases, highlighting the need for integrated skin and general healthcare in the elderly.
21 citations
,
July 2017 in “Journal of Cosmetic and Laser Therapy” Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.
17 citations
,
June 2017 in “Journal of pharmaceutical sciences” Researchers developed a nanomedicine for acne treatment that delivers medication with less irritation and is non-irritating for oily skin.
13 citations
,
March 2013 in “International Journal of Cosmetic Science” AcSDKP may help prevent skin and hair aging and promote their growth.
12 citations
,
July 2020 in “International Journal of Pharmaceutics” Iron oxide nanoparticles improve skin penetration and drug release for hair loss treatment.
9 citations
,
November 2018 in “Journal of cosmetic dermatology” Orobanche rapum extract rejuvenates skin and protects skin bacteria, leading to healthier skin.
5 citations
,
August 2014 in “Pharmaceutical Development and Technology” Propylene glycol and ethanol increase finasteride skin absorption, sodium lauryl sulfate doesn't.
2 citations
,
December 2022 in “Journal of toxicologic pathology” Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
2 citations
,
March 2020 in “International Journal of Molecular Sciences” Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.
May 2026 in “Organoid Research” Hydrogel-based methods improve skin organoid development for medical and research applications.
April 2026 in “Journal of Pharmaceutical Investigation” Nanotechnology could improve treatment for scars and atopic dermatitis by targeting skin issues more effectively.
March 2026 in “Aging Research” Personalized anti-aging strategies are important, considering genetics and lifestyle.
February 2026 in “Frontiers in Bioengineering and Biotechnology” Liposome-based systems improve skin wound healing effectively.
November 2025 in “Frontiers in Immunology” Immune cells are crucial for normal skin development and their dysfunction can cause skin disorders.
March 2025 in “Asian Journal of Beauty and Cosmetology” Microspicule cosmetics improve skin whitening, pores, and barrier strength.