research Keratin K15 as a Biomarker of Epidermal Stem Cells
Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.
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research Dynamic Signals for Hair Follicle Development and Regeneration
Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
research Apoptosis and cutaneous biology
Apoptosis is crucial for healthy skin and treating skin diseases.
research Adipose-derived stem cells alleviate radiation-induced dermatitis by suppressing apoptosis and downregulating cathepsin F expression
Adipose-derived stem cells help heal radiation skin damage by reducing cell death and inflammation.
research Module-based complexity formation: periodic patterning in feathers and hairs
The conclusion is that understanding how feathers and hairs pattern can help in developing hair regeneration treatments.
research Embryonic keratinization in vertebrates in relation to land colonization
Keratinization in embryos helped vertebrates adapt to land by forming a protective skin barrier.
research Molecular cloning of two novel types of peptidylarginine deiminase cDNAs from retinoic acid‐treated culture of a newborn rat keratinocyte cell line
Two new enzymes, PAD-R11 and PAD-R4, were cloned and showed activity, with PAD-R11 resembling epidermal enzymes.
research Unveiling the Roots of Monogenic Genodermatoses: Genotrichoses as a Paradigm
New gene identification techniques have improved the understanding and classification of inherited hair disorders.
research MSCs and their exosomes: a rapidly evolving approach in the context of cutaneous wounds therapy
MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.
research Expression Profiling Reveals Genes Involved in the Regulation of Wool Follicle Bulb Regression and Regeneration in Sheep
The research identified genes and pathways important for sheep wool growth and shedding.
research Deciphering principles of morphogenesis from temporal and spatial patterns on the integument
The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
research Cutaneous stem cells: something new and something borrowed
Epidermal stem cells maintain skin health through specific niches and signaling pathways.
research Identification of novel glucocorticoid receptor-regulated genes involved in epidermal homeostasis and hair follicle differentiation
Glucocorticoid receptors help regulate genes important for skin health and hair growth.
research Integrated miRNA-mRNA analysis reveals regulatory pathways underlying the curly fleece trait in Chinese tan sheep
Researchers found genes and microRNAs that control curly fleece in Chinese Tan sheep.
research Osteopontin Gene is Expressed in the Dermal Papilla of Pelage Follicles in a Hair-Cycle-Dependent Manner
The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.
research Can dermal delivery of therapeutics be improved using thermoresponsive nanogels?
Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.
research Establishment of keratinocyte cell lines from human hair follicles
Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.
research Hair growth promoting effect of bioactive extract from deer antler velvet-loaded niosomes and microspicules serum
Deer antler velvet serum helps hair grow and is safe for skin.
research Conditional Knockout in Mice Reveals the Critical Roles of Ppp2ca in Epidermis Development
PP2Acα is essential for proper hair and skin development.
research Wnt/β-catenin signaling promotes aging-associated hair graying in mice
A certain signaling pathway in mice, when increased, causes hair to gray by depleting the cells that give hair its color.
research Morphologic and immunologic characterization of a canine isthmus mural folliculitis resembling pseudopelade of humans
Dogs have a skin condition like human pseudopelade, causing hair loss that doesn't improve with treatment.
research Kyoto Rhino Rats Derived by ENU Mutagenesis Undergo Congenital Hair Loss and Exhibit Focal Glomerulosclerosis
A new rat strain with a specific gene mutation causes hair loss and kidney issues.
research Molecular elements of the regulatory control of keratin filament modulator AHF/trichohyalin in the hair follicle
The study concluded that a protein important for hair strength is regulated by certain molecular processes and is affected by growth phases.
research Lupus comédonien
A man was diagnosed with a rare form of lupus after showing unique skin symptoms that responded well to treatment.
research 4 Anti-androgens in gynaecological practice
Cyproterone acetate is effective for treating hirsutism and acne in women by blocking androgens in the skin and also works as a contraceptive.
research Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis
GLI1 might protect against the start of skin cancer and is not linked to cancer severity.
research Highly Upregulated Lhx2 in the Foxn1−/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche
The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.
research Bald thigh syndrome in sighthounds—Revisiting the cause of a well-known disease
Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.
research Evo Devo of the Vertebrates Integument
The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
research Nutritional Dermatoses in the Hospitalized Patient
Poor nutrition can lead to skin diseases in hospitalized patients and should be quickly identified and treated.