September 2019 in “Journal of Investigative Dermatology” Scientists used stem cells to create a model of the skin disease Epidermolysis Bullosa simplex, which helped them understand its molecular mechanisms and could aid in finding treatments.
September 2017 in “Journal of Investigative Dermatology” Mackerel fermented fish oil protects skin cells from damage by UVB light.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Applying the anti-cancer drug Bortezomib to skin can promote hair growth and increase hair proteins through the GATA-3 factor.
November 2013 in “Annales de Dermatologie et de Vénéréologie” Cinnamon essential oil can cause severe or unusual skin reactions, with cinnamaldehyde being the main allergen.
June 2010 in “Expert Review of Dermatology” Scientists found key proteins and genes that affect skin and hair health, and identified potential new treatments for hair loss, skin disorders, and wound healing.
58 citations
,
July 2005 in “Molecular and Cellular Biology” A specific gene segment can make mouse skin cells glow, helping study hair growth and gene effects.
28 citations
,
July 2008 in “Developmental Biology” Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
28 citations
,
February 1999 in “Journal of Investigative Dermatology” Urokinase, a type of protein, helps skin cells multiply faster, especially in newborn mice.
10 citations
,
August 2020 in “Current protocols in stem cell biology” Scientists developed a way to create skin and hair cells from human stem cells, which could help treat burns and restore hair.
3 citations
,
August 2013 in “Stem cells” Certain inhibitors applied to the skin can promote hair growth by maintaining a key hair growth signal.
November 2024 in “Journal of Investigative Dermatology” Scalp hair follicle cells help protect and heal skin in certain skin conditions.
September 2021 in “Research Square (Research Square)” Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.
December 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Papulopustular rosacea is an inflammatory skin condition treatable with lifestyle changes and medications.
April 2017 in “Journal of Investigative Dermatology” Deleting Crif1 in mouse skin disrupts skin balance and hair growth.
June 2001 in “Proceedings of SPIE” Low energy laser therapy effectively treats certain skin conditions and improves recovery time without side effects.
26 citations
,
June 2024 in “Frontiers in Immunology” SOCS1 and SOCS3 help control skin inflammation and are important for developing treatments for skin diseases.
292 citations
,
October 1985 in “The Journal of Cell Biology” Keratins and filaggrin change as fetal skin develops, marking key stages of skin formation.
133 citations
,
June 1993 in “Molecular and Cellular Biology” The human K5 promoter controls specific gene expression in skin cells, with key regulatory elements near the TATA box.
111 citations
,
June 2002 in “The EMBO Journal” Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.
66 citations
,
April 1995 in “The journal of cell biology/The Journal of cell biology” A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.
52 citations
,
October 2007 in “Molecular Therapy” Injecting lentiviral vectors into early gestation mice effectively targets skin stem cells for potential gene therapy.
50 citations
,
September 2011 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.
48 citations
,
May 1991 in “The journal of investigative dermatology/Journal of investigative dermatology” Trichohyalin is also found in the outer layers of normal human skin.
32 citations
,
December 2014 in “Cold Spring Harbor Perspectives in Medicine” Disruptions in epidermal polarity genes can lead to skin diseases.
21 citations
,
September 2010 in “Cancer Prevention Research” Overactive signaling in hair follicles can lead to skin cancer.
19 citations
,
December 2016 in “PLOS ONE” Early-stage skin cells help regenerate hair follicles, with proteins SDF1, MMP3, biglycan, and LTBP1 playing key roles.
17 citations
,
February 2015 in “International Journal of Molecular Sciences” A special mix from certain skin cells can help hair grow by making hair root cells grow faster and activating growth signals.
12 citations
,
January 2018 in “Biomaterials Science” Softer hydrogel surfaces help maintain hair growth-related functions in skin cells.
9 citations
,
May 2023 in “Inflammation Research” New small molecule drugs show promise in treating complex skin diseases but need more safety research.
8 citations
,
April 1990 in “PubMed” Minoxidil helps hair growth by prolonging cell division in skin cells.