165 citations
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December 2004 in “Differentiation” BMP signaling is crucial for skin and hair growth.
73 citations
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June 2001 in “Endocrinology” Prolactin affects when mice shed and grow hair.
32 citations
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January 2010 in “Journal of Dermatological Science” Reduced EGFR signaling delays hair cycle and reduces fat growth, but hair development remains normal.
28 citations
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March 2011 in “Journal of Investigative Dermatology” Hair follicles help guide nerve growth, improving touch recovery in skin grafts.
27 citations
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December 1997 in “Archives of Dermatological Research” Rat dermal papilla cells have unique properties and interact differently with their environment compared to other skin cells.
14 citations
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June 2001 in “Endocrinology” Prolactin affects when mice shed and grow hair.
1 citations
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July 2016 in “Livestock science” Nerve growth factor helps cashmere goat hair cells grow and is more active during the hair growth phase.
1 citations
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March 2012 in “Journal of Dermatological Science” Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.
July 2024 in “Journal of Investigative Dermatology” Linalool in fragrances may harm hair follicles and contribute to hair loss.
July 2023 in “Frontiers in Veterinary Science” Melatonin helps hair grow by activating the RORα receptor in goats.
April 2017 in “Journal of Investigative Dermatology” Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” The mutant HR bmh protein mis-localizes in cells, affecting skin and hair development.
Activating CB1 can reduce keratin levels, potentially helping manage psoriasis and aid wound healing.
Activating cannabinoid receptor 1 may help manage psoriasis by reducing certain keratins.
July 2004 in “British Journal of Dermatology” The document concludes that accurate diagnosis and treatment are crucial in dermatology, and it presents various findings on skin conditions and treatments.
January 2004 in “Journal of Guangzhou University of Traditional Chinese Medicine” Androgen receptor abnormalities may contribute to hair loss in androgenetic alopecia.
252 citations
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January 2008 in “Trends in Endocrinology and Metabolism” Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.
66 citations
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January 2001 in “Vitamins and hormones” Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.
176 citations
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January 2003 in “Journal of Investigative Dermatology” Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.
142 citations
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March 2019 in “Frontiers in Cellular Neuroscience” The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
139 citations
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September 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.
119 citations
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July 2016 in “Annals of the New York Academy of Sciences” Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
88 citations
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May 2020 in “Clinical therapeutics” Stress can worsen skin diseases by affecting immune cells, hormones, and neurotransmitters in the skin.
71 citations
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February 2006 in “Clinics in Dermatology” Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.
66 citations
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February 2013 in “PeerJ” Activating cannabinoid receptor 1 reduces certain keratin levels, potentially aiding psoriasis treatment.
60 citations
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November 2023 in “Biology” Aging skin causes inflammation that affects the whole body.
49 citations
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April 2006 in “Journal of Investigative Dermatology” TRPV1 helps regulate hair growth cycles.
15 citations
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May 2016 in “Die Pharmazie” Nanostructured lipid carriers deliver lidocaine to the skin better than nanoethosomes.
10 citations
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September 2023 in “Metabolites” Iron is crucial for skin health, with specific proteins recycling it to support skin functions and prevent its release.
7 citations
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October 2010 in “Medical Hypotheses” Alopecia areata may involve stress-related changes affecting hormone receptors, leading to reduced cortisol production.