research The Multi-Faceted Role of Gut Microbiota in Alopecia Areata
Gut bacteria may influence hair loss in alopecia areata.
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research Tyrosine kinase Inhibitors in Dermatology: A Systemic Review
Tyrosine kinase inhibitors show promise in treating some skin diseases but their definitive role in dermatology is still unclear.
research Inflammation in androgenetic alopecia and hair loss: linking neurosciences-endocrinology-dermatology
Hair loss in men may be caused by inflammation triggered by hormones, and treatments reducing inflammation could potentially promote hair growth.
research Stigmatizing attitudes towards facial psoriasis, atopic dermatitis, vitiligo and alopecia areata
People often have negative attitudes towards facial skin conditions, with vitiligo seen most positively and psoriasis viewed most negatively.
research Efficacy, Safety, and Tolerability of a Triple Wavelength Laser for Hair Reduction in Indian Women: A Prospective Clinical Study
The triple wavelength laser is effective, safe, and well-tolerated for hair reduction in Indian women.
research Global Epidemiology of Telogen Effluvium after COVID-19 Pandemic: A Systematic Review and Modeling Study
Telogen effluvium increased globally after COVID-19, especially in Asian and Latin regions.
research eLife assessment: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2
Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.
research Mesenchyme governs hair follicle induction
The mesenchyme can start hair growth, but the exact signal that causes this is still unknown.
research 138 Characterization of xenobiotic metabolizing enzymes of a reconstructed human epidermal model from adult hair follicles
The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.
research Low-level light therapy and hair loss
Low-level light therapy is FDA-approved for male pattern hair loss, increases hair count and strength, and is considered safe for use.
research An Analysis of the Correlation between Alopecia and Chief Complaints
Hair loss is significantly linked to symptoms like dry hair, scalp issues, addiction to tobacco or coffee, anxiety, and digestive problems.
research Tofacitinib 2% ointment, a topical Janus kinase inhibitor, for the treatment of alopecia areata: A pilot study of 10 patients
Tofacitinib 2% ointment helped hair regrow in 3 out of 10 patients with alopecia areata, but caused side effects like scalp irritation and raised cholesterol in some.
research Oral Isotretinoin in HIV-Positive Women with Acne: Report of Three Cases
Isotretinoin effectively treated severe acne in HIV-positive women, with improved skin and CD4 counts, but some experienced side effects like skin dryness and hair loss.
research An in vivo method for the detection of somatic mutations at the cellular level in mice
A new method can detect mutations in mice by observing changes in hair follicle cells.
research Erosive pustular dermatosis of the scalp following topical ingenol mebutate for actinic keratoses
Two elderly men developed scalp inflammation after using a gel for skin lesions, which healed with treatment except for some permanent hair loss.
research Erosive pustular dermatosis of the scalp - is it really a rare condition?
Erosive pustular dermatosis of the scalp may not be as rare as previously thought.
research Apremilast and tofacitinib exert differential effects in the humanized mouse model of alopecia areata
Tofacitinib was more effective than apremilast in treating hair loss in a mouse model of alopecia areata.
research Erythema multiforme sparing regressing herpes zoster lesion: “Reverse isotopic phenomenon?”
A patient's skin rash did not affect the area where a previous viral rash was healing, suggesting a rare immune response.
research Essential Fatty Acid Deficiency (EFAD) in a Patient with Vascular Ehlers Danlos Syndrome (EDS-4) (P12-053-19)
A patient with Ehlers-Danlos Syndrome improved after treatment for fat malabsorption and essential fatty acid deficiency.
research 646 SOX4 is essential for melanoma tumorigenesis
SOX4 is crucial for the development of melanoma.
research Lichen planopilaris after hair transplantation
Oral minoxidil improved male baldness, but had side effects; certain antibiotics effectively treated a rare scalp condition; hair transplants might trigger another scalp condition.
research Editorial Board
Biotin is important for metabolism, with specific daily intake recommendations, and deficiency can cause health problems.
research The Double-Edged Sword of Epidermal Growth Factor Receptor Inhibitor: Rash as Toxicity and Prognostic Marker
A 50-year-old man undergoing treatment with the epidermal growth factor receptor inhibitor (EGFRI) lapatinib for stage 2 breast carcinoma developed a papulopustular rash, a common side effect of EGFRIs, affecting 50-100% of patients. This rash, part of the 'PRIDE' complex, includes various cutaneous adverse effects such as xerosis and eczema. The patient was treated with doxycycline and hydrocortisone cream, showing significant improvement within a week. Acneiform eruptions, which lack comedones, may serve as a potential marker for therapeutic response to EGFRI drugs, although evidence is inconsistent. The rash typically appears within 1-2 weeks of therapy, peaks at 3-4 weeks, and subsides gradually. Patients are advised on sun protection and gentle skincare to manage symptoms.
research Insulin resistance and chronic inflammatory dermatoses
Insulin resistance significantly contributes to the development and severity of certain chronic skin diseases.
research Photo-responsive fibers as artificial hairs in an in-vitro model for transdermal drug delivery
Artificial hair fibers improve drug delivery accuracy through skin models.
research Canine demodicosis: A case report and successful recovery at Izatnagar, Bareilly
The dog fully recovered from demodicosis after treatment with Bravecto and supportive care.
research Effective Scald Wound Functional Recovery Patch Achieved by Molecularly Intertwined Electrical and Chemical Message in Self-Adhesive Assemblies
The patch helps heal minor scald wounds by providing electrical and chemical signals to boost recovery.
research Efficacy of oral isotretinoin in the treatment of acne vulgaris
Isotretinoin effectively treats acne, with most patients experiencing clear skin.
research Plain language summaries
Doctors need more training in skin cancer screening, a new treatment is effective for a skin condition, better diagnosis methods for skin cancer are available, hair loss in women may be linked to hormones and cholesterol, certain skin care products might cause hair loss, babies' skin gets weaker after birth, and a gene mutation might be linked to eczema.
research Immunhistochemische und biochemische Untersuchungen zur Expression von epithelialen Keratinen in klinisch unveränderter Pferdehaut und Fußhaut von Kaltblutpferden mit Warzenmauke-Syndrom
Diseased horse foot skin shows increased keratin expression, similar to wound healing in mammals.