research Epidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures
Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
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research Neuroendocrine Controls of Keratin Expression in Human Skin
Neurohormones help control skin health and could treat skin disorders.
research Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease
The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
research Skin structure
Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
research Chapter 6 Fetal Skin Wound Healing
Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
research Defining Skin Fibroblastic Cell Types Beyond CD90
The conclusion is that CD90 is not a specific marker for fibroblast subtypes and better methods are needed to identify them.
research 874 Elevated expression of osteopontin splice variants in nonmelanoma skin cancer compared to normal skin and adult keratinocytes
Nonmelanoma skin cancers have higher levels of certain osteopontin variants than normal skin.
research 1456 Tensor effect of anigozanthos flavidus flower extract: Modulation of tenascin-X to regenerate the skin
Anigozanthos Flavidus flower extract helps regenerate skin and reduce wrinkles.
research Deletion of adipocyte Sine Oculis Homeobox Homolog 1 prevents lipolysis and attenuates skin fibrosis
Removing SIX1 in fat cells reduces skin fibrosis.
research Reduced cell cohesiveness of outgrowths from eccrine sweat glands delays wound closure in elderly skin
Older people's sweat glands are less effective at helping skin wounds heal due to weaker cell connections.
research Defining stem cell dynamics and migration during wound healing in mouse skin epidermis
Stem cells help heal wounds by rapidly dividing and migrating to the wound edge.
research Intragenic deletion in the Desmoglein 4 gene underlies the skin phenotype in the Iffa Credo “hairless” rat
A gene deletion causes the "hairless" trait in Iffa Credo rats.
research Transcriptome sequencing reveals the expression profiles of lncRNAs and mRNAs in goat skin tissues with different types of wool coats
The study identified key genes and pathways that influence goat wool quality and growth.
research A new look into an old problem: keratins as tools to investigate determination, morphogenesis, and differentiation in skin.
Keratin expression reflects cell organization and differentiation, not causes it.
research 1396 Interferon-24 regulates the expression of MMP1 and dermal collagen of the skin
IL-24 contributes to skin aging by increasing collagen-degrading enzymes and decreasing collagen production when exposed to air pollution.
research Biomaterials for dermal substitutes
The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.
research Controlled Rigidity Nanolipogel-Mediated Topical Delivery of Fucosterol for Treating Androgenic Alopecia through Follicle Targeting, Promoting Angiogenesis and Inhibiting Inflammation
A new method using nanolipogels with fucosterol can help regrow hair by targeting follicles, reducing inflammation, and improving blood flow.
research Green‐Prepared Magnesium Silicate Sprays Enhance the Repair of Burn‐Skin Wound and Appendages Regeneration in Rats and Minipigs
Magnesium Silicate Sprays help heal burn wounds and regrow skin features better than commercial products.
research A Niche Above: A Novel Modality of Stem Cell Regulation in Mammalian Skin Epidermis
Skin cell behavior is influenced by the tightness of nearby cells, affecting their growth and development.
research 1454 Identification of Fetuin A as a potential modulator of scar formation
Fetuin A may increase collagen production and promote scarring.
research Use of platelet rich plasma for skin rejuvenation
Platelet-rich plasma (PRP) is effective and safe for improving skin appearance.
research Skin, hair and beyond: the impact of menopause
Menopause causes dry skin, wrinkles, and hair changes, with hormone therapy helping but not recommended just for these issues.
research Treatment of scleromyxoedema with hydroxychloroquine
Hydroxychloroquine helped improve scleromyxoedema in patients, but caused side effects in some.
research Intrinsic versus Extrinsic Aging: A Histopathological, Morphometric and Immunohistochemical Study of Estrogen Receptor β and Androgen Receptor
The study concluded that both estrogen and androgen receptors, which decrease with age, are linked to skin aging and may be hormonally regulated.
research Matricellular Proteins in the Homeostasis, Regeneration, and Aging of Skin
Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
research Bioengineered Skin Intended as In Vitro Model for Pharmacosmetics, Skin Disease Study and Environmental Skin Impact Analysis
Bioengineered skin models help reduce animal testing and advance research in cosmetics and skin disease.
research Specific Attention Areas in Scar Management: Specific Scar Management Depending on Anatomical Features (Face, Hair, Breast, Hand, Joints, Foot)
Tailored scar treatments are needed for different body areas to improve appearance and function.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research The Rotterdam Study: 2016 objectives and design update
The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.
research Mechanical and biological properties of keratose biomaterials
Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.