21 citations
,
July 2017 in “Journal of Cosmetic and Laser Therapy” Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.
16 citations
,
December 2006 in “Expert Review of Dermatology” Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
7 citations
,
April 2013 in “Clinical and Experimental Dermatology” Tianeptine, an antidepressant, may prevent stress-induced hair loss in mice.
1 citations
,
September 2012 in “TURKDERM” Stress may affect alopecia areata, but it's not a confirmed trigger.
May 2026 in “The EMBO Journal” Skin aging can be slowed by targeting cells, hormones, and the microbiome.
38 citations
,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
11 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.
8 citations
,
September 2016 in “Reviews in Endocrine and Metabolic Disorders” Skin health and diseases are closely linked to metabolic processes.
1 citations
,
May 2022 in “Frontiers in medicine” Metformin helps improve skin regeneration by increasing the growth of skin stem cells.
Folate salts penetrate skin well and improve wound healing, suggesting potential for skin treatments.
February 2026 in “Frontiers in Bioengineering and Biotechnology” Liposome-based systems improve skin wound healing effectively.
January 2023 in “Fundamental toxicological sciences” Mozuku seaweed fucoidan can inhibit harmful skin bacteria growth.
July 2021 in “Journal of dermatology research and therapy” Using combined treatments can help manage acne by targeting the bacteria and skin changes that cause it.
October 2012 in “Humana Press eBooks” Grape seed extract is good for skin care, with antioxidant, anti-inflammatory, and anti-cancer effects.
788 citations
,
February 2007 in “Nature” The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
306 citations
,
April 2019 in “International Journal of Molecular Sciences” The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
305 citations
,
February 2007 in “Hormone and metabolic research” Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.
280 citations
,
July 2018 in “Antioxidants” Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.
277 citations
,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
276 citations
,
December 2017 in “Journal of Dermatological Science” The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
268 citations
,
April 2009 in “International Journal of Pharmaceutics” Niosomes improve minoxidil skin delivery for hair loss treatment.
225 citations
,
April 2018 in “Journal of Investigative Dermatology” Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.
211 citations
,
May 2018 in “Trends in cell biology” Different types of skin cells play specific roles in development, healing, and cancer.
205 citations
,
July 2009 in “Journal of Dermatological Science” Male and female skin differ in many ways, which could lead to gender-specific skin treatments.
202 citations
,
August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
156 citations
,
August 2016 in “Journal of controlled release” Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
155 citations
,
May 2016 in “Nature communications” Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.
151 citations
,
November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
150 citations
,
January 2018 in “Burns & Trauma” Bioprinting could improve wound healing but needs more development to match real skin.
141 citations
,
January 1984 in “Journal of The American Academy of Dermatology” Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.